Results 51 to 60 of about 88,321 (214)

Identification of Barriers to Access Endovascular Treatment for Acute Ischemic Stroke in the Health Care System of Mexico: Results From a National Survey Among Endovascular Neurologists

open access: yesFrontiers in Neurology, 2021
Background: Providing endovascular treatment (EVT) access for acute ischemic stroke (AIS) is a challenge in Latin America. Even though the Mexican Endovascular Reperfusion Registry (MERR) and the RESILIENT trial have demonstrated the feasibility of EVT ...
Fernando Gongora-Rivera   +3 more
doaj   +1 more source

Characterization of Defect Distribution in an Additively Manufactured AlSi10Mg as a Function of Processing Parameters and Correlations with Extreme Value Statistics

open access: yesAdvanced Engineering Materials, EarlyView.
Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt   +8 more
wiley   +1 more source

Herramientas digitales para la edición del teatro aurisecular: el informe de una tentativa a partir de EVT (Edition Visualization Technology)

open access: yesRevista de Humanidades Digitales
El objetivo de este artículo es dar cuenta de un intento de digitalización llevado a cabo en el contexto de la edición del teatro aurisecular, y más concretamente del teatro de Lope de Vega, con el fin de hacer balance de los avances realizados en ...
Anna Abate, Lorenzo Bocchi
doaj   +1 more source

Adaptation in tunably rugged fitness landscapes: The Rough Mount Fuji Model

open access: yes, 2014
Much of the current theory of adaptation is based on Gillespie's mutational landscape model (MLM), which assumes that the fitness values of genotypes linked by single mutational steps are independent random variables. On the other hand, a growing body of
Krug, Joachim   +2 more
core   +1 more source

Statistics of the separation between sliding rigid rough surfaces: Simulations and extreme value theory approach [PDF]

open access: yes, 2019
When a rigid rough solid slides on a rigid rough surface, it experiences a random motion in the direction normal to the average contact plane. Here, through simulations of the separation at single-point contact between self-affine topographies, we ...
Malthe-Sørenssen, Anders   +4 more
core   +2 more sources

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

open access: yesAdvanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou   +10 more
wiley   +1 more source

The Laws of Ine. Report of a Digital Edition of a Renaissance Manuscript

open access: yesUmanistica Digitale
This report describes the implementation of a digital edition of the Laws of Ine as part of my MA final dissertation, contained in MS Additional 43703, transcribed in 1562 by the English antiquarian Laurence Nowell.
Fabio Soncin
doaj   +1 more source

Towards Trace Metrics via Functor Lifting [PDF]

open access: yes, 2015
We investigate the possibility of deriving metric trace semantics in a coalgebraic framework. First, we generalize a technique for systematically lifting functors from the category Set of sets to the category PMet of pseudometric spaces, showing under ...
Baldan, Paolo   +3 more
core   +5 more sources

Endometrial Assembloid Model Reveals Endometrial Gland Development Regulation by Estradiol‐Driven WNT7B Suppression

open access: yesAdvanced Science, EarlyView.
This study developed a 3D endometrial assembloid model to study how uterine glands form and develop. They discovered key interactions between different cell types and identified WNT7B as a regulator controlled by estradiol‐mediated TGFβ1‐VDR interaction.
Xintong Li   +12 more
wiley   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

open access: yesAdvanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang   +12 more
wiley   +1 more source

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