Results 231 to 240 of about 101,518 (273)

Phosphorylation of Ewing's sarcoma protein (EWS) and EWS-Fli1 in response to DNA damage

Biochemical Journal, 2009
In Ewing's sarcomas, chromosomal translocations cause the N-terminal domain of the EWS (Ewing's sarcoma protein) to fuse with the DNA-binding domains of the Ets (E26 transformation-specific) family of transcription factors. Here we show that EWS and EWS-Fli1 (Friend leukaemia virus integration 1), the fusion most frequently found in Ewing's sarcomas ...
Klevernic, Iva V., Morton, Simon, Davis, Roger J., Cohen, Philip   +3 more
openaire   +3 more sources

Targeting the EWS–FLI1 transcription factor in Ewing sarcoma

Cancer Chemotherapy and Pharmacology, 2015
Preclinical data indicate there is strong synergism of action against Ewing sarcoma in sequential treatment with trabectedin followed by irinotecan and it appears to be related to a selective blockade of the transcription factor EWS-FLI1. This combination was evaluated in Ewing sarcoma patient who was progressing with standard therapies.Trabectedin was
Tancredi, R, Zambelli, A, DaPrada, G A, Fregoni, V, Pavesi, L, Riccardi, A, Burdach, S, Grohar, P J, D'Incalci, M   +8 more
openaire   +4 more sources

Ewing's tumour

Clinical Radiology, 1971
A study of 244 histologically proven cases of Ewing's Tumour is presented, illustrating its clinical behaviour and radiological appearances. 170 patients were treated between 1941 and 1964 by radiation, surgery, chemotherapy or combinations of these methods. Nine cases survived for more than 5 years.
openaire   +2 more sources

EWS–ETS oncoproteins: The linchpins of Ewing tumors

Gene, 2005
Ewing tumors, which comprise Ewing's sarcoma and peripheral primitive neuroectodermal tumors, are highly aggressive and mostly affect children and adolescents. Their molecular signature is a chromosomal translocation leading to the generation of EWS-ETS (or very rarely FUS-ETS) fusion proteins that are capable of transforming cells.
openaire   +2 more sources

Ewing's tumor of the mandible

Oral Surgery, Oral Medicine, Oral Pathology, 1993
A primary Ewing's tumor in the mandible is reported, and the diagnostic imaging features of this lesion are discussed. Modalities used included panoramic and plain films, computed tomography, and 99mTc-MDP scintigraphy.
GURBUZER, B, YENICI, O, TUROGLU, HT, OZDAMAR, S, YALCIN, S, SADIKOGLU, Y   +5 more
openaire   +4 more sources

Pigmenturia in a ewe

Journal of the American Veterinary Medical Association, 2023
Mary Jane, Drake, Rachael, Gately, Francisco O, Conrado, Leslie C, Sharkey   +3 more
openaire   +2 more sources

Hypocalcaemia in ewes

Veterinary Record, 1985
J, Kemp, R M, Maff, G D, Wilson
openaire   +2 more sources

EWING'S SARCOMA

Orthopedics, 1995
T A, Damron, H N, Shih, L E, Wold, R A, McLeod, F H, Sim   +4 more
openaire   +2 more sources

Reproductive Performance of Triplet-Bearing Ewes on Commercial Farms and Research Priorities Identified by Sheep Producers to Improve the Survival of Triplet-Bearing Ewes and Their Lambs

Animals, 2023
Andrew Thompson, Amy Lockwood, P R Kenyon   +2 more
exaly  

Effect of age and diet on carcass and meat quality in ewes

Heliyon, 2023
Alicia Grajales-Lagunes, Alejandro E Relling, Alfonso Juventino Chay-Canul   +2 more
exaly