Ethical considerations of genetic and genomic testing in pediatric oncology: A narrative review
Abstract Genomics—and genomic testing in particular—has transformed oncology, facilitating both targeted therapies and personalized care. In pediatric oncology, unique clinical and ethical considerations arise. Compared with adults, children and adolescents are affected by more limited evidence regarding test performance, variant interpretation, and ...
Brittany L. Greene, Jonathan M. Marron
wiley +1 more source
Molecular and immunohistochemical characterisation of matched primary and metastatic Ewing sarcomas
Die Diagnostik von Ewing-Sarkomen (ES) basiert auf molekularpathologischen und immunhistochemischen Analysen. In einer früheren Arbeit wurde ein Patient mit zwei separaten ES beschrieben, in denen unterschiedliche EWSR1-Translokationen nachgewiesen ...
Wentker, D. (Dennis)
core
TRAIL receptor signaling and therapeutic option in bone tumors: the trap of the bone microenvironment [PDF]
Tumor Necrosis Factor-Related Apoptosis Inducing Ligand (TRAIL/TNFSF10) has been reported to specifically induce malignant cell death being relatively nontoxic to normal cells. Since its identification 15 years ago, the antitumor activity and therapeutic
Heymann, D. +4 more
core +3 more sources
Melanotic Neuroectodermal Tumour of Infancy: A Rare Brain Tumour of Childhood [PDF]
Melanotic neuroectodermal tumour of infancy is a rare, mostly benign but locally aggressive tumour of neural crest cellorigin occurring in infants. The most commonly affected anatomic site is the maxilla. Such tumours of the brain and skull are very rare.
Bari, Muhammad Ehsan +5 more
core +1 more source
M E, Horowitz, M G, Tsokos, T F, DeLaney
openaire +2 more sources
AVN944 Elicits Apoptotic Responses and Impedes Tumorigenic Potential in Ewing's Sarcoma Cells. [PDF]
Lim H, Lee S, Kim G, Lee EJ, Kim J.
europepmc +1 more source
Extraosseous Ewing's Sarcoma of the Chest Wall: A Case Report and Review of Literature. [PDF]
Feng Y, Liang Y, Wang R, Chen Z.
europepmc +1 more source
Ewing's Sarcoma of the Frontal Bone with Intracranial Extension. [PDF]
Ahuja S, Malik S, Ahluwalia C.
europepmc +1 more source
Extraskeletal Ewing's Sarcoma/Primitive Neuroectodermal Tumor of the Breast in a Young Woman. [PDF]
Sharmin S +6 more
europepmc +1 more source

