Results 71 to 80 of about 7,060 (163)

Patient‐Derived Organoids and High‐Throughput Drug Screening: Advancing Functional Precision Medicine in Pediatric Cancer

Organ Medicine, EarlyView.
Yiyang Bao, Xingfei Chen, Jingyi Huang, Xiaoyu Lin, Yanlai Tang   +4 more
wiley   +1 more source

Osteosarcoma of the Jaws in Latin America: A Retrospective Multicenter Series of 119 Cases

Oral Diseases, EarlyView.
ABSTRACT Objective Epidemiological and survival data on osteosarcoma of the jaws (OSJ) in Latin America remain scarce. We characterized the clinicopathological, radiographic, treatment‐related, and survival features of OSJ in Latin America. Methods This multicenter case series involved 22 institutions from Brazil, Chile, Argentina, Colombia, Venezuela,
Victor Zanetti Drumond, José Alcides Almeida de Arruda, Mariana Villaroel‐Dorrego, Leonardo Amaral Dos Reis, Gerhilde Callou Sampaio, Lauren Frenzel Schuch, Carolina Louzada Menna‐Barreto, Manoela Domingues Martins, Paula Celeghini Goulart, Guilherme Gomes Souza, Fabrício Tinôco Alvim de Souza, Warley Oliveira Silva, Karina Cordero‐Torres, Rolando Morales‐Espinosa, René Panico, Gerardo Gilligan, Federico Garola, Carlos Marcelo Cerullo, Nicolás Leonardi, Javier Giménez, Verónica Flück, Ángeles Castrillo, Laura Leguina, Claudia Patricia Peña‐Vega, Juan Pablo Rodríguez‐Mora, Kallana Mezzomo‐Faccin, Ricardo Luiz Cavalcanti de Albuquerque‐Junior, Rogério Gondak, Mônica Simões Israel, Pollianna Muniz Alves, Amanda Claudino Gomes, Cassiano Francisco Weege Nonaka, Michel Campos Ribeiro, Elismauro Francisco de Mendonça, Victor Hugo Lopes de Oliveira Moreira, Diego Antônio Costa Arantes, Israel Leal Cavalcante, Eveline Turatti, Roberta Barroso Cavalcante, Giovanna Tacchi, Ana Paula Neutzling Gomes, Karen Müller Bubolz, Adriana Etges, María Natalia González Umpiérrez, Natalia Fernanda Tancredi Cueto, Aurita Verónica Beovide‐Cortegoso, Ronell Bologna‐Molina, Saray Aranda‐Romo, Francisco Javier Tejeda‐Nava, Lucas Guimarães Abreu, Bruno Augusto Benevenuto de Andrade, Ricardo Alves Mesquita   +51 more
wiley   +1 more source

Adult Primary Spinal Epidural Extraosseous Ewing’s Sarcoma: A Case Report and Review of the Literature

Case Reports in Neurological Medicine, 2016
Background. Extraosseous Ewing’s sarcoma in the spinal epidural space is a rare malignancy, especially in adults. Case Presentation. A 40-year-old male presented with back pain and urinary hesitancy.
Mark Bustoros, Cheddhi Thomas, Joshua Frenster, Aram S. Modrek, N. Sumru Bayin, Matija Snuderl, Gerald Rosen, Peter B. Schiff, Dimitris G. Placantonakis   +8 more
doaj   +1 more source

An Interaction with Ewing’s Sarcoma Breakpoint Protein EWS Defines a Specific Oncogenic Mechanism of ETS Factors Rearranged in Prostate Cancer

Cell Reports, 2016
Summary: More than 50% of prostate tumors have a chromosomal rearrangement resulting in aberrant expression of an oncogenic ETS family transcription factor.
Vivekananda Kedage, Nagarathinam Selvaraj, Taylor R. Nicholas, Justin A. Budka, Joshua P. Plotnik, Travis J. Jerde, Peter C. Hollenhorst   +6 more
doaj   +1 more source

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Computational modelling of cardiac fibroblast signalling reveals a key role for Ca2+ in driving atrial fibrillation‐associated fibrosis

The Journal of Physiology, EarlyView.
Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani, Haibo Ni, Jeffrey J Saucerman, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi   +5 more
wiley   +1 more source

Asymptomatic Cardiotoxicity After High‐Dose Anthracycline Treatment in Sarcoma Patients Assessed by Biomarkers and Echocardiography

International Journal of Cancer, Volume 159, Issue 11, Page 2755-2765, 1 December 2026.
ABSTRACT Treatment of sarcoma includes high‐dose anthracyclines, which can cause cardiotoxicity. This study assesses the correlation of cardiac biomarkers and echocardiographic parameters on asymptomatic cardiotoxicity in sarcoma patients treated with anthracyclines.
Elissa A. S. Polomski, Frank M. Speetjens, J. Wouter Jukema, Julius C. Heemelaar, Michiel A. J. van de Sande, Hans Gelderblom, M. Louisa Antoni   +6 more
wiley   +1 more source

Ewing Sarcoma in Infants and Children Under 2 Years of Age: A French Retrospective Study

Pediatric Blood &Cancer, Volume 73, Issue 11, November 2026.
ABSTRACT Ewing sarcoma, the second most common primary bone cancer in children, requires intensive treatment that may lead to significant long‐term sequelae, particularly in infants. We retrospectively analyzed data from 1621 French patients treated between 1988 and 2015 within the EW88/93/97 or EE99 trials, focusing on 17 infants diagnosed before 24 ...
Elodie Verdier, Nathalie Cozic, Marie‐Dominique Tabone, Gaelle Pierron, Perrine Marec‐Berard, Sarah Winter, Gabriel Revon‐Rivière, Cyril Lervat, Dominique Plantaz, Marie‐Pierre Castex, Gregory Guimard, Estelle Thebaud, Stephanie Proust, Laure Saumet, Natacha Entz‐Werle, Sophie Taque, Cécile Vérité, Marta Jimenez, Nathalie Gaspar   +18 more
wiley   +1 more source

A Personalised Vaccination Program Based on Immune Reconstitution in Paediatric Cancer Survivors

Acta Paediatrica, Volume 115, Issue 11, Page 2603-2615, November 2026.
ABSTRACT Aims Paediatric cancer survivors often experience treatment‐induced immunosuppression, requiring post‐treatment revaccination. However, immune recovery timelines vary, and current revaccination guidelines, largely based on data of varied quality derived from studies on acute‐lymphoblastic‐leukaemia (ALL), may not be applicable across all ...
Menucha Jurkowicz, Raz Somech, Dan Dominissini, Nathan Keller, Efrat Dresner, Michal Paret, Gilad Sherman, Guy Katzenellenbogen, Elina Gelman, Keren Asraf, Ram Doolman, Atar Lev, Amos J. Simon, Helly Vernitsky, Assaf Barg, Hana Golan, Amos Toren, Michal Stein   +17 more
wiley   +1 more source

Evolving role of proton therapy in contemporary oncology

Cancer, Volume 132, Issue 20, 15 October 2026.
Abstract Proton therapy offers a distinct physical advantage over photon radiotherapy through the Bragg peak dose concentration in target with both lower integral dose and finite path length, and sharper penumbra as compared to photons, collectively reducing radiation exposure to surrounding normal tissues and potentially improving the therapeutic ...
Emily S. Lebow, Helen A. Shih
wiley   +1 more source