Results 51 to 60 of about 16,801 (243)

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

open access: yesFEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah   +8 more
wiley   +1 more source

ANALISIS KEBIJAKAN PUBLIK DALAM PEMERIKSAAN KINERJA

open access: yesJurnal Tata Kelola dan Akuntabilitas Keuangan Negara, 2018
One of the issues in performance audit is what method to be used if the auditor wants to gain an understanding of policies underlying the entity's activities. This study aims to provide an understanding regarding the policy cycle and its development; to
Denny Wahyu Sendjaja   +2 more
doaj  

Prospective Life Cycle Assessment of Hydrogen: A Systematic Review of Methodological Choices

open access: yesEnergies
This systematic review examines methodological choices in assessing hydrogen production and utilisation technologies using prospective life cycle assessments (LCA) between 2010 and 2022, following PRISMA guidelines.
Gustavo Ezequiel Martinez   +4 more
doaj   +1 more source

A contemporary investigation of causality between the primary government budget deficit and the ex ante real long term interest rate in the US

open access: yesPSL Quarterly Review, 2012
Using error-correction model (ECM) estimation, this study empirically examines, for theUS, the causality relationship between the federal government budget deficitand the ex ante real long term interest rate.
Richard J. Cebula
doaj   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

open access: yesFEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

On Ex Ante Contractualism

open access: yesJournal of Ethics and Social Philosophy, 2018
Ex ante contractualism holds that in situations involving risk we ought to act in accordance with principles that license the action that satisfies the strongest individual claim, where those claims are a function of the expected value that a given policy gives each person ex ante. I here challenge ex ante contractualism on contractualist grounds.
openaire   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Piling up or Packaging Policies? An Ex-Post Analysis of Modal Shift in Four Cities

open access: yesEnergies, 2018
Recently, there has been wider acknowledgement that sustainable urban mobility will not be triggered by one ‘silver bullet’ policy, or by piling up various policies, but requires a deliberate package of policies.
Marc Dijk, Moshe Givoni, Karen Diederiks
doaj   +1 more source

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