Results 41 to 50 of about 21,523 (310)

Impacts of intellectual property provisions in trade treaties on access to medicine in low and middle income countries: a systematic review

open access: yesGlobalization and Health, 2019
Background We present a systematic review describing ex-ante and ex-post evaluations of the impacts of intellectual property provisions in trade treaties on access to medicine in low and middle income countries.
Md. Deen Islam   +5 more
doaj   +1 more source

Influence of Project Governance on Opportunistic Behavior: Taking a Dynamic Perspective

open access: yesBuildings, 2022
The importance of project governance in curbing opportunistic behavior (OB) has been clearly established in the project literature. Although contract governance and trust are considered critical factors that explain project governance, there is a lack of
Wenjing Han, Yilin Yin
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Kajian Perkiraan Dampak Rencana Pembangunan Pelabuhan Onshore Bagi Masyarakat di Pesisir Kota Pekalongan

open access: yesJurnal Pembangunan Wilayah dan Kota
Pelabuhan Perikanan Nusantara Pekalongan (PPNP) mengalami penurunan kinerja akibat banjir rob dan penurunan tanah. Pemerintah Kota Pekalongan berupaya mengatasi permasalahan tersebut melalui rencana pembangunan Pelabuhan Onshore untuk meningkatkan sektor
Tia Dianing Insani, Iwan Rudiarto
doaj   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Data for absorption, evaluation and effectiveness of R&D projects in Greece

open access: yesData in Brief, 2021
This data article presents primary data for the absorption, evaluation, and effectiveness of 1949 research projects implemented by 3259 research institutions in the framework of funding actions of the operational programmes of the Partnership Agreement ...
Evangelos Makryvelios, George Mavrotas
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Método dinâmico da Escola de Estocolmo

open access: yesBrazilian Journal of Political Economy, 2010
Dynamic method of the Stockholm School. The development of the dynamic method is considered the biggest contribution of the Stockholm School. The objective of this review-article is to show as this method contributed for the Alternative Theory of Money ...
Fernando Nogueira da Costa
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

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