Results 51 to 60 of about 3,436 (168)

Researcher–Entrepreneur Relationship and Performance of Innovative Startups

International Journal of Finance &Economics, EarlyView.
ABSTRACT Many innovative startups are joint ventures between researchers and entrepreneurs, who collaborate in R&D and product commercialization. Government policies such as grants, subsidies, and patent licensing fees act as Pigouvian subsidies, incentivizing R&D by bridging the gap between the social and private returns of innovation.
Yangguang Huang, Helen Hui
wiley   +1 more source

Motive and Opportunity: Order Choice in a Limit Order Book With Dispersed Information

International Journal of Finance &Economics, EarlyView.
ABSTRACT We test predictions of market microstructure theory relating to the determinants of order choice in a limit order book where information is dispersed among traders. Using an experimental limit order book, with a large state space, we find that informed traders exhibit patience, compatible with the ‘waiting game’ behaviour described in Foster ...
James Steeley, Charles Schnitzlein, Patricia Chelley‐Steeley   +2 more
wiley   +1 more source

Strategies and mechanisms of precision genome engineering: From gene editing to genome writing

iMetaOmics, EarlyView.
In this review, we examined the progression of genome manipulation from stochastic nuclease‐mediated cutting toward precise editing and programmable genome writing. We discussed tools like multi‐kilobase RNA‐guided integrators and Artificial Intelligence (AI)‐designed effectors and showed how these advances enable researchers to treat genomes as ...
Kerui Huang, Jianhong Tian, Wenyan Zhao, Siqin Zhang, Lixuan Xiang, Meiqing Yang, Lu Liu, Yazhou Huang, Ningyun Zhang, Lei Sun, Peng Xie, Nanyu Kuang, Hong Zhou, Chengfeng Qiu, Jun Yan, Xiaocheng Jiang, Qiang Tu, Yun Wang, Haoliang Hu, Youming Zhang   +19 more
wiley   +1 more source

Foreign body ingestions in children and adolescents: A position paper of the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) endoscopy special interest group

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Foreign body (FB) ingestion is a relatively frequent occurrence in the pediatric population with multiple potential sequelae. Appropriate intervention may range from urgent endoscopic retrieval to watchful waiting, with multiple variables influencing the decision.
Oren Ledder, Raoul Furlano, Alexandra Papadopoulou, Dominique Schluckebier, Andreia Nita, Christos Tzivinikos, Salvatore Oliva, Simona Faraci, Luigi Dall'oglio, Marco Deganello Saccomani, Priya Narula, Iva Hojsak, Jorge Amil Dias, Vasiliki Spyropoulou, Lorenzo Norsa, Gokhan Baysoy, Claudio Romano, Matjaž Homan, Mike Thomson   +18 more
wiley   +1 more source

The Use of Blue Light as an Antimicrobial Treatment Against Staphylococcus aureus: A Systematic Review

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Background Staphylococcus aureus (S. aureus) is a major cause of skin, wound, and device‐related infections. Blue light (405–470 nm), shows promise for treating this organism. However, the translatability, dosing parameters, safety, and effectiveness remain unclear, and no systematic review currently exists.
Alexander Idrogo‐Lam, Kofi Owusu‐Ansah, Eric Cotter, Lisa Cotter   +3 more
wiley   +1 more source

Homogenous Cell Transplantation Trials in Parkinson's Disease: A Systematic Review and Meta‐Analysis

Movement Disorders Clinical Practice, EarlyView.
Abstract Background The transplantation of homogenous cells has emerged as an investigational strategy for Parkinson's disease (PD), offering an alternative to symptomatic treatment. Objective We performed a systematic review and meta‐analysis to assess its clinical efficacy and safety.
Nolan Reinisch, Athena Mancini, Adham Elsherbini, Jason Yuen, Andres Lozano   +4 more
wiley   +1 more source

Artificial Intelligence for Identifying Tumor‐Reactive CD8+ T Cells: Biological Principles, Computational Advances, and Future Directions

Med Research, EarlyView.
This review details a three‐stage paradigm shift for tumor‐reactive CD8+ T‐cell identification: decoding transcriptomic states, deciphering clonal functional efficacy, and molecular‐level therapeutic TCR design. Addressing translational hurdles and generative AI “scientific blind spots”—such as missing catch bonds—we present a visionary roadmap.
Chao Yang, Yingying Sun, Yan Zhang, Yifen Shi, Zhiwen Shi   +4 more
wiley   +1 more source

Insights into the thermal ecology, physiology, and behavior of a threatened ectothermic specialist from a warming and drying ecoregion. [PDF]

Biol Open
Blais BR, Mazzamuto MV, Koprowski JL.
europepmc   +1 more source

Information Design for Early‐Stage Dose‐Finding Trials

Naval Research Logistics (NRL), EarlyView.
ABSTRACT To enhance enrollment rates in early‐stage dose‐finding clinical trials, we propose an information design approach, where the clinical investigator (CI) commits to an information releasing mechanism (IRM) based on the treatment's uncertain efficacy and toxicity to encourage patients to participate in the trial.
Amin Khademi, Ningyuan Chen
wiley   +1 more source

A renewed perspective on TCA intermediate cis-aconitate: mechanisms and therapeutic options against influenza virus. [PDF]

EMBO Mol Med
Claus C, Kovacevic I.
europepmc   +1 more source