Results 91 to 100 of about 7,452,553 (207)

Enforcement Design and Targeted Deterrence in Professional Sports: Evidence From NBA Anti‐Flopping Reforms

open access: yesManagerial and Decision Economics, EarlyView.
ABSTRACT This paper examines strategic responses to alternative enforcement designs in professional basketball. Using NBA player‐level panel data, we study two anti‐flopping reforms: ex post financial fines introduced in 2012–2013 and in‐game technical fouls implemented in 2023–2024.
Martín ‐Legendre   +5 more
wiley   +1 more source

Artificial Intelligence for Identifying Tumor‐Reactive CD8+ T Cells: Biological Principles, Computational Advances, and Future Directions

open access: yesMed Research, EarlyView.
This review details a three‐stage paradigm shift for tumor‐reactive CD8+ T‐cell identification: decoding transcriptomic states, deciphering clonal functional efficacy, and molecular‐level therapeutic TCR design. Addressing translational hurdles and generative AI “scientific blind spots”—such as missing catch bonds—we present a visionary roadmap.
Chao Yang   +4 more
wiley   +1 more source

Molecular Glue Degraders in Early Development for Cancer Therapy

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Molecular glue degraders are an emerging class of small molecule allosteric modulators that induce or stabilize protein‐protein interactions, enabling targeted degradation of previously intractable proteins. By redirecting E3 ligases to recognize neosubstrates, proteins that are not typically recognized by a specific E3 ubiquitin ligase, they ...
E. Sila Ozdemir   +4 more
wiley   +1 more source

Noninvasive or minimally invasive neuromodulation in animal models of acute ischemic stroke: A systematic review and meta‐analysis

open access: yesNeuroprotection, EarlyView.
This systematic review and meta‐analysis assessed the cytoprotective effects of neuromodulation in preclinical models of ischemic stroke. Pooled analyses showed that neuromodulation significantly reduced infarct volume and improved neurological outcomes.
Igor Caitano Salles   +7 more
wiley   +1 more source

Bayesian Causal Methods for Environmental Accountability Studies with Heterogeneous Effects. [PDF]

open access: yesCurr Environ Health Rep
Zorzetto D   +6 more
europepmc   +1 more source

Mobilizing Presence across Borders: Devotion to Papua New Guinea's Blessed Peter To Rot in Australia

open access: yesOceania, EarlyView.
ABSTRACT This article engages with the conjunctures between migration and religion by focusing on the celebration of Papua New Guinea's ‘National Patron Saint’, the Blessed Peter To Rot, in the Australian diaspora. Both in Sydney and Brisbane, Catholic Papua New Guinea (PNG) migrants have been ‘relocating’ PNG shrines, regalia, relics and ritual ...
Anna‐Karina Hermkens
wiley   +1 more source

Third annual transplant AI symposium: from organ matching to digital twins. [PDF]

open access: yesFront Transplant
Ramesh D   +7 more
europepmc   +1 more source

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