Results 101 to 110 of about 7,457,259 (243)

Multi‐omics–driven precision medicine

open access: yesiMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li   +20 more
wiley   +1 more source

Dignity's Dilemma: Categorical Objections to Autonomous Weapons and Their Pacifist Entailments

open access: yesJournal of Applied Philosophy, EarlyView.
ABSTRACT Dignity objections to autonomous weapon systems are prominent in contemporary military ethics, yet their theoretical foundations remain underexamined. This article reconstructs those foundations, showing what categorical dignity objections require to function as absolute prohibitions.
Timothy Dubber
wiley   +1 more source

The Regulator and the Judge: The Optimal Mix in TheControl of Environmental Risk [PDF]

open access: yes
Nous considérons une firme qui génère un risque pour l'environnment via son activité industrielle et qui a une information privée à la fois sur son effort de précaution et sur le montant de ses actifs. Nous étudions l'interaction entre l'audit ex ante de
Jérôme Pouyet   +2 more
core  

The Use of Blue Light as an Antimicrobial Treatment Against Staphylococcus aureus: A Systematic Review

open access: yesLasers in Surgery and Medicine, EarlyView.
ABSTRACT Background Staphylococcus aureus (S. aureus) is a major cause of skin, wound, and device‐related infections. Blue light (405–470 nm), shows promise for treating this organism. However, the translatability, dosing parameters, safety, and effectiveness remain unclear, and no systematic review currently exists.
Alexander Idrogo‐Lam   +3 more
wiley   +1 more source

DDRed in Liberia: Youth Remarginalisation or Reintegration? [PDF]

open access: yes
This report questions mainstream approaches to the reintegration of youthful ex-combatants. In Liberia, the disarmament and demobilisation was implemented quite effectively, but several questions can be asked about the components of reintegration and ...
Morten Bøås, Ingunn Bjørkhaug
core  

Homogenous Cell Transplantation Trials in Parkinson's Disease: A Systematic Review and Meta‐Analysis

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background The transplantation of homogenous cells has emerged as an investigational strategy for Parkinson's disease (PD), offering an alternative to symptomatic treatment. Objective We performed a systematic review and meta‐analysis to assess its clinical efficacy and safety.
Nolan Reinisch   +4 more
wiley   +1 more source

Enforcement Design and Targeted Deterrence in Professional Sports: Evidence From NBA Anti‐Flopping Reforms

open access: yesManagerial and Decision Economics, EarlyView.
ABSTRACT This paper examines strategic responses to alternative enforcement designs in professional basketball. Using NBA player‐level panel data, we study two anti‐flopping reforms: ex post financial fines introduced in 2012–2013 and in‐game technical fouls implemented in 2023–2024.
Martín ‐Legendre   +5 more
wiley   +1 more source

Statement: [Account of W.B. Post and Lincoln of August 21, 1863]

open access: yes, 2012
Handwritten account of W.B. Post and Lincoln of August 21, 1863, signed W.B. Post, 4 pages.
Post, W.B.
core  

Artificial Intelligence for Identifying Tumor‐Reactive CD8+ T Cells: Biological Principles, Computational Advances, and Future Directions

open access: yesMed Research, EarlyView.
This review details a three‐stage paradigm shift for tumor‐reactive CD8+ T‐cell identification: decoding transcriptomic states, deciphering clonal functional efficacy, and molecular‐level therapeutic TCR design. Addressing translational hurdles and generative AI “scientific blind spots”—such as missing catch bonds—we present a visionary roadmap.
Chao Yang   +4 more
wiley   +1 more source

Ex ante and ex post institutional convergence: Case of the post-Soviet space [PDF]

open access: yes
: The paper discusses the interaction of ex ante and ex post institutional convergence in the post-Soviet world, i.e. 12 members of the Commonwealth of Independent States.
Libman, Alexander
core  

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