Results 91 to 100 of about 1,237,463 (291)
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Exact Algorithms for Kayles [PDF]
, 2011 In the game of Kayles, two players select alternatingly a vertex from a given graph G, but may never choose a vertex that is adjacent or equal to an already chosen vertex. The last player that can select a vertex wins the game. In this paper, we give an exact algorithm to determine which player has a winning strategy in this game.
Bodlaender, H.L., Kratsch, D.
openaire +2 more sources
Exact algorithms via monotone local search [PDF]
Proceedings of the forty-eighth annual ACM symposium on Theory of Computing, 2016 We give a new general approach for designing exact exponential-time algorithms for subset problems . In a subset problem the input implicitly describes a family of sets over a universe of size n and the task is to determine whether the family contains at least one set.
Fedor V. Fomin +3 more
openaire +3 more sources
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Modified Gerchberg–Saxton (G-S) Algorithm and Its Application
Entropy, 2020 The Gerchberg–Saxton (G-S) algorithm is a phase retrieval algorithm that is widely used in beam shaping and optical information processing. However, the G-S algorithm has difficulty obtaining the exact solution after iterating, and an approximate ...
Tieyu Zhao, Yingying Chi
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Asymptotically exact streaming algorithms
, 2014 We introduce a new computational model for data streams: asymptotically exact streaming algorithms. These algorithms have an approximation ratio that tends to one as the length of the stream goes to infinity while the memory used by the algorithm is restricted to polylog(n) size. Thus, the output of the algorithm is optimal in the limit.
Heinrich, Marc +2 more
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Efficiency comparison of exact and approximate algorithms for solving set covering problem
Advanced Engineering Research, 2017 Introduction. A quite general class of practical tasks is guided by the set covering problem: schedules building, layout of service stations, and creation of electronic circuits.
Igor S. Konovalov +2 more
doaj +1 more source