Results 101 to 110 of about 395,539 (297)

Modelling the optical and radiative properties of freshly emitted light absorbing carbon within an atmospheric chemical transport model [PDF]

Atmospheric Chemistry and Physics, 2010
Light absorbing carbon (LAC) aerosols have a complex, fractal-like aggregate structure. Their optical and radiative properties are notoriously difficult to model, and approximate methods may introduce large errors both in the interpretation of aerosol ...
M. Kahnert
doaj  

Conditional inference with a complex sampling: exact computations and Monte Carlo estimations

, 2012
In survey statistics, the usual technique for estimating a population total consists in summing appropriately weighted variable values for the units in the sample.
Coquet, François, Lesage, Éric
core   +1 more source

Discrete-time Quantum Walks in random artificial Gauge Fields

, 2015
Discrete-time quantum walks (DTQWs) in random artificial electric and gravitational fields are studied analytically and numerically. The analytical computations are carried by a new method which allows a direct exact analytical determination of the ...
Debbasch, F., Di Molfetta, G.
core   +3 more sources

Towards exact geometric computation

Computational Geometry, 1997
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Second-order adjoint sensitivity analysis procedure (SO-ASAP) for computing exactly and efficiently first- and second-order sensitivities in large-scale linear systems:II. Illustrative application to a paradigm particle diffusion problem

, 2014
This work presents an illustrative application of the second-order adjoint sensitivity analysis procedure (SO-ASAP) to a paradigm neutron diffusion problem, which is sufficiently simple to admit an exact solution, thereby making transparent the ...
Cacuci, Dan G.
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Two-fluid compressible simulations on GPU cluster

ESAIM: Proceedings and Surveys, 2014
In this work we propose an efficient finite volume approximation of two-fluid flows. Our scheme is based on three ingredients. We first construct a conservative scheme that removes the pressure oscillations phenomenon at the interface.
Helluy Philippe, Jung Jonathan
doaj   +1 more source