Results 81 to 90 of about 395,539 (297)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Finding Octonionic Eigenvectors Using Mathematica

open access: yes, 1998
The eigenvalue problem for 3x3 octonionic Hermitian matrices contains some surprises, which we have reported elsewhere. In particular, the eigenvalues need not be real, there are 6 rather than 3 real eigenvalues, and the corresponding eigenvectors are ...
Ablamowicz   +16 more
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

General Formulation of Inverse Substructuring Method for Multicoordinate Coupled System

open access: yesAdvances in Mechanical Engineering, 2014
A frequency response function- (FRF-) based direct decoupling method is proposed and applied to inverse analysis of a multicoordinate coupled system. The general formulation of inverse substructuring method for multicoordinate coupled multisubstructure ...
Jun Wang   +3 more
doaj   +1 more source

Vortices in the two-dimensional Simple Exclusion Process

open access: yes, 2008
We show that the fluctuations of the partial current in two dimensional diffusive systems are dominated by vortices leading to a different scaling from the one predicted by the hydrodynamic large deviation theory.
B. Derrida   +23 more
core   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

An exact mathematical description of computation with transient spatiotemporal dynamics in a complex-valued neural network

open access: yesCommunications Physics
Networks throughout physics and biology leverage spatiotemporal dynamics for computation. However, the connection between structure and computation remains unclear. Here, we study a complex-valued neural network (cv-NN) with linear interactions and phase-
Roberto C. Budzinski   +9 more
doaj   +1 more source

A study of light scattering by wavelength-sized particles covered by much smaller grains using the superposition T-matrix method

open access: yesAtti della Accademia Peloritana dei Pericolanti : Classe di Scienze Fisiche, Matematiche e Naturali, 2011
By using the results of a direct, numerically exact solution of the Maxwell equations we analyze the behavior of the light scattering characteristics for polydisperse spherical particles covered with a large number of smaller grains.
J. M. Dlugach   +3 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Direction of bifurcation for some non-autonomous problems

open access: yesElectronic Journal of Differential Equations, 2012
We study the exact multiplicity of positive solutions, and the global solution structure for several classes of non-autonomous two-point problems. We present two situations where the direction of turn can be computed rather directly. As an application,
Philip Korman
doaj  

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