Results 231 to 240 of about 656,028 (291)

Controllability changes pain perception by increasing the precision of expectations. [PDF]

Nat Commun
Habermann M, Büchel C.
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Light-Induced Neuron-Like Bursts. [PDF]

J Phys Chem Lett
Kumar J, Fenollosa R, Rivera-Sierra G, Kim SY, Bisquert J.   +4 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Lesion-Induced Changes to the Network Controllability of the Right Pars Triangularis in Aphasia. [PDF]

Neurobiol Lang (Camb)
Stoll H, Kelkar A, Turkeltaub PE, Hamilton RH, Hamilton RH, Coslett B, Medaglia JD.   +6 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Generative pretraining for drug molecule design with bidirectional structure-property optimization. [PDF]

Commun Chem
Song Y, He S, Bo X, Zhang Z.
europepmc   +1 more source

Thalamic organization differentially contributes to clinical conditions in epilepsy. [PDF]

Commun Med (Lond)
Zhang Q, Javidi SS, Ankeeta A, Sperling MR, Zhang Z, Tracy JI.   +5 more
europepmc   +1 more source

Active disambiguation guides inferring controllability and cause in social interactions. [PDF]

Nat Commun
Spiering L, Trier HA, O'Reilly JX, Kolling N, Wittmann MK, Rushworth MFS, Scholl J.   +6 more
europepmc   +1 more source

Evolvable AI: Threats of a new major transition in evolution. [PDF]

Proc Natl Acad Sci U S A
Müller V, Steels L, Szathmáry E.
europepmc   +1 more source