Results 11 to 20 of about 35,570 (198)

Efficient enumeration of solutions produced by closure operations

, 2019
In this paper we address the problem of generating all elements obtained by the saturation of an initial set by some operations. More precisely, we prove that we can generate the closure of a boolean relation (a set of boolean vectors) by polymorphisms ...
Mary, Arnaud, Strozecki, Yann
core   +3 more sources

A transfer matrix approach to the enumeration of plane meanders

, 2000
A closed plane meander of order $n$ is a closed self-avoiding curve intersecting an infinite line $2n$ times. Meanders are considered distinct up to any smooth deformation leaving the line fixed. We have developed an improved algorithm, based on transfer
, (Kholodenko A L, Alon N, Arnold V, Derrida B, Di Francesco P, Di Francesco P, Di Francesco P, Enting I G, Guttmann A J, Hoffmann K, Iwan Jensen, Jensen I, Kholodenko A L, Knuth D E, Ko K H, Koehler J E, Lunnon W, Mehlhorn K, Poincaré H, Pratt V R, Semenoff G W, Touchard J, {Di Francesco P   +23 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Numerical Estimation of the Asymptotic Behaviour of Solid Partitions of an Integer

, 2003
The number of solid partitions of a positive integer is an unsolved problem in combinatorial number theory. In this paper, solid partitions are studied numerically by the method of exact enumeration for integers up to 50 and by Monte Carlo simulations ...
Andrews G E, Atkin A O L, Bender C M, Bhatia D P, Bortz A B, Brak R, Elser V, Guttmann A J, Hardy G H, Knuth D E, MacMahon P A, Martin J L, R Rajesh, Stanley R P, Temperley H N V, Temperley H N V, van Rensburg E J J, Ville Mustonen, Widom M, Wright E M, Wright E M, Wu F Y   +21 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Enumeration of self-avoiding walks on the square lattice

, 2004
We describe a new algorithm for the enumeration of self-avoiding walks on the square lattice. Using up to 128 processors on a HP Alpha server cluster we have enumerated the number of self-avoiding walks on the square lattice to length 71.
Caracciolo S, Caracciolo S Guttmann A J Jensen I Pelissetto A Rogers A N Sokal A D, Cardy J L, Cardy J L, Conway A R, Enting I G, Guttmann A J, Guttmann A J, Guttmann A J, Iwan Jensen, Jensen I, Jensen I, Jensen I, Jensen I, Jensen I P M A Sloot D Abramson A V Bogdanov J J Dongarra A Y Zomaya Y E Gorbachev, Knuth D E, Knuth D E, Lin K Y, Madras N, Nienhuis B, Owczarek A L, Privman V, Richard C, Saleur H   +23 more
core   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Spanning trees in random series-parallel graphs [PDF]

, 2015
By means of analytic techniques we show that the expected number of spanning trees in a connected labelled series-parallel graph on $n$ vertices chosen uniformly at random satisfies an estimate of the form $s \varrho^{-n} (1+o(1))$, where $s$ and ...
Ehrenmüller, Julia, Rué, Juanjo
core   +3 more sources

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source