Results 211 to 220 of about 323,983 (267)

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Longevity is heritable and negatively genetically correlated between the sexes in yellow-bellied marmots. [PDF]

Evol Lett
Dumas MN, Krasnay B, Chabot CA, Fraser Franco M, Gagnon É, Isaksson E, Lécuyer L, Masoero G, Molina P, Montiglio PO, Saneeibajgiran S, St Lawrence S, Blumstein DT, Martin JGA.   +13 more
europepmc   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Systemic Cytokine Patterns and Histologic Disease Spectrum in Inflammatory Bowel Disease. [PDF]

Curr Issues Mol Biol
Martinos N, Kroupis C, Gypari M, Kranidiotis G, Karakoidas C, Konstantinou M, Lazaris AC, Thomopoulou GE.   +7 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

RE: Evaluating benefit-to-burden ratios of the established and emerging colorectal cancer screening strategies. [PDF]

J Natl Cancer Inst
Ebner DW, Estes C, Limburg PJ.
europepmc   +1 more source

Testing for hereditary cancer genes in men: a missed opportunity for cancer prevention. [PDF]

Front Oncol
Szmyd C, LaFleur M, Cantu-Weinstein A, Zhang J, Sun N, Sha Y, Saben JL, ElNaggar AC, Liu MC, Parmar S, Souter V.   +10 more
europepmc   +1 more source

RDA-PSO: A Computational Method to Quantify the Diffusive Dispersal of Insects. [PDF]

Bull Math Biol
Mrad L, Lega J.
europepmc   +1 more source

Timing of dexamethasone initiation during controlled ovarian stimulation and live birth after IVF/ICSI: a retrospective cohort study. [PDF]

Front Endocrinol (Lausanne)
Zhang L, Tang B, Qin Y, Lu X, Tang J, Peng A.   +5 more
europepmc   +1 more source