Results 91 to 100 of about 2,430,570 (319)

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

An Exact Solution of the Binary Singular Problem

open access: yesJournal of Function Spaces, 2014
Singularity problem exists in various branches of applied mathematics. Such ordinary differential equations accompany singular coefficients. In this paper, by using the properties of reproducing kernel, the exact solution expressions of dual singular ...
Baiqing Sun   +3 more
doaj   +1 more source

Exact Solution of the Multi-Allelic Diffusion Model

open access: yes, 2005
We give an exact solution to the Kolmogorov equation describing genetic drift for an arbitrary number of alleles at a given locus. This is achieved by finding a change of variable which makes the equation separable, and therefore reduces the problem with
Baxter, G., Blythe, R. A., McKane, A. J.
core   +2 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Fifty Years of the Exact Solution of the Two-Dimensional Ising Model by Onsager [PDF]

open access: yes, 1995
The exact solution of the two-dimensional Ising model by Onsager in 1944 represents one of the landmarks in theoretical physics. On the occassion of the fifty years of the exact solution, we give a historical review of this model.
Bhattacharjee, Somendra M.   +1 more
core   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

The Constant Astigmatism Equation. New Exact Solution

open access: yes, 2013
In this paper we present a new solution for the Constant Astigmatism equation.
Manganaro, Natale, Pavlov, Maxim V.
core   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Exact solution of A-D Temperley-Lieb Models

open access: yes, 1995
We solve for the spectrum of quantum spin chains based on representations of the Temperley-Lieb algebra associated with the quantum groups ${\cal U}_q(X_n } for $X_n = A_1,B_n,C_n$ and $D_n$.
A Lima-Santos   +11 more
core   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

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