Results 111 to 120 of about 547,457 (313)

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

Three-Dimensional Unsteady Stagnation-Point Flow and Heat Transfer Impinging Obliquely on a Flat Plate with Transpiration

open access: yesJournal of Applied Fluid Mechanics, 2016
In this study, an exact solution of the Navier-Stokes and energy equations is obtained for the problem of unsteady three-dimensional stagnation point flow and heat transfer of viscous, incompressible fluid on a flat plate.
Hadi Haddad   +2 more
doaj  

Exact Solution for Water Evaporation During CO2 Injection

open access: yesWater Resources Research
The objective of this study is to develop an analytical model for 1D gas‐water flow with evaporation of water into the mobile gas phase. The evaporation rate is proportional to the fluid‐fluid interfacial area, which is a function of the water saturation.
T. Russell, P. Bedrikovetsky
doaj   +1 more source

Reproducing kernel method for a class of weakly singular Fredholm integral equations

open access: yesJournal of Taibah University for Science, 2018
Numerical methods for solving integral equations have been the focus of much research, including reproducing kernel methods. We present a new algorithm to solve weakly singular Fredholm integral equations (WSFIEs). The advantage of this method is that it
Azizallah Alvandi, Mahmoud Paripour
doaj   +1 more source

The exact formulas for calculating deflection and forces in the rods of the ’Molodechno’ truss with an arbitrary number of panels

open access: yesИнженерно-строительный журнал, 2016
We have obtained an analytical expression for the deflection and forces in the rods of a flat truss of beam type in the elastic stage. We found that the induction method, which has been tested for a wide class of two-dimensional elastic and regular ...
M.N. Kirsanov
doaj   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

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