Results 141 to 150 of about 4,500,655 (305)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Exact solution to quantum dynamical activity [PDF]
The quantum dynamical activity constitutes a thermodynamic cost in trade-off relations such as the quantum speed limit and the quantum thermodynamic uncertainty relation. However, calculating the quantum dynamical activity has been a challenge.
Nishiyama, Tomohiro, Hasegawa, Yoshihiko
core +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
elrm: Software Implementing Exact-Like Inference for Logistic Regression Models [PDF]
Exact inference is based on the conditional distribution of the sufficient statistics for the parameters of interest given the observed values for the remaining sufficient statistics.
Brad McNeney, David Zamar, Jinko Graham
core
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Exact solution for flat scale-invariant cosmology
, 2022 Se obiene una solución exacta para la cosmología espacialmente plana de escala invariante propuesta recientemente por Maeder. No se encuentran diferencias respecto a la solución numérica.
Jesus, J.F.
core
AxiomsThe homotopy perturbation method (HPM) is one of the recent fundamental methods for solving differential equations. However, checking the accuracy of this method has been ignored by some authors in the literature.
Mona Aljoufi
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Numerical Studied for Solving Fuzzy Integro-Differential Equations via Caputo Fractional Derivative
Academic Science JournalIn this paper, we extended some numerical methods to solve fuzzy integro differential equations. The considered problem involves the fractional Caputo derivatives under some conditions on the ordered. As we combine Euler's method with composite Simpsons
Ruaa N. Abduallah, Rokan khaji
doaj +1 more source