Results 251 to 260 of about 2,550,692 (341)
FEBS Open Bio, EarlyView.CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
FEBS Open Bio, EarlyView.HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
FEBS Open Bio, EarlyView.We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
Nonlinear dispersion of a pollutant ejected into a channel flow
Open Physics, 2011 Gorder Robert, Vajravelu Kuppalapalle
doaj +1 more source
An exact solution for R2,eff in CPMG experiments in the case of two site chemical exchange.
J Magn Reson, 2014 Baldwin AJ.
europepmc +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Calculation of the pH Values of Aqueous Systems Containing Carbonic Acid and Significance for Natural Waters, Following (Near-)Exact and Approximated Solutions: The Importance of the Boundary Conditions. [PDF]
MoleculesRosso A, Vione D.
europepmc +1 more source
Hierarchical Structure of Azbel-Hofstader Problem and its Asymptotycally Exact Solution
, 1999 P. Wiegmann
openalex +1 more source