Results 51 to 60 of about 1,121 (263)
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Multipole structure of compact objects
Physical Sciences and Technology, 2017 We analyze the applications of general relativity in relativistic astrophysics in order to solve the problem of describing the geometric and physical properties of the interior and exterior gravitational and electromagnetic fields of compact objects. We
H. Quevedo
doaj
Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, EarlyView.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Renyi Type Holographic Dark Energy
Journal of New TheoryDark energy is one of the prominent mysteries of the universe that still awaits a solution. One of the plausible ways to collect data about any formation or understand its information capacity is to investigate the entropy of that formation.
Arzu Aktaş, İhsan Yılmaz
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FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Critical Phenomena in Gravitational Collapse
Living Reviews in Relativity, 1999 As first discovered by Choptuik, the black hole threshold in the space of initial data for general relativity shows both surprising structure and surprising simplicity.
Gundlach Carsten
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Symmetry, Integrability and Geometry: Methods and Applications, 2011 The non-autonomous chiral model equation for an m×m matrix function on a two-dimensional space appears in particular in general relativity, where for m=2 a certain reduction of it determines stationary, axially symmetric solutions of Einstein's vacuum ...
Aristophanes Dimakis +2 more
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Entropy, 2013 The many moments model for dense gases and macromolecular fluids is considered here, where the upper order moment is chosen in accordance to the suggestions of the non-relativistic limit of the corresponding relativistic model.
Sebastiano Pennisi +2 more
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Gravitational shock waves and scattering amplitudes
Journal of High Energy Physics, 2020 We study gravitational shock waves using scattering amplitude techniques. After first reviewing the derivation in General Relativity as an ultrarelativistic boost of a Schwarzschild solution, we provide an alternative derivation by exploiting a novel ...
Andrea Cristofoli
doaj +1 more source
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source