Results 51 to 60 of about 77,425 (318)

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Stability of Schwarzschild singularity in non-local gravity

open access: yesPhysics Letters B, 2017
In a previous work, it was shown that all Ricci-flat spacetimes are exact solutions for a large class of non-local gravitational theories. Here we prove that, for a subclass of non-local theories, the Schwarzschild singularity is stable under linear ...
Gianluca Calcagni, Leonardo Modesto
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

General Relativity, the Cosmological Constant and Modular Forms

open access: yes, 2002
Strong field (exact) solutions of the gravitational field equations of General Relativity in the presence of a Cosmological Constant are investigated.
Kraniotis, G. V., Whitehouse, S. B.
core   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

How Extra Symmetries Affect Solutions in General Relativity

open access: yesUniverse, 2020
To get exact solutions to Einstein’s field equations in general relativity, one has to impose some symmetry requirements. Otherwise, the equations are too difficult to solve.
Aroonkumar Beesham, Fisokuhle Makhanya
doaj   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Compact objects with scalar charge embedded in a magnetic or electric field in Einstein–Maxwell-dilaton theories

open access: yesEuropean Physical Journal C: Particles and Fields
In this paper, we generalize the Schwarzschild–Melvin solution within Einstein–Maxwell-dilaton theories to include non-null scalar charges, while remaining embedded in a magnetic or electric field à la Melvin.
Olivier Minazzoli, Maxime Wavasseur
doaj   +1 more source

Volume Integral Theorem for Exotic Matter

open access: yes, 2004
We answer an important question in general relativity about the volume integral theorem for exotic matter by suggesting an exact integral quantifier for matter violating Averaged Null Energy Condition (ANEC). It is checked against some well known static,
H. G. Ellis   +6 more
core   +2 more sources

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

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