Results 71 to 80 of about 77,425 (318)

Off-diagonal cosmological solutions in emergent gravity theories and Grigory Perelman entropy for geometric flows

open access: yesEuropean Physical Journal C: Particles and Fields, 2021
We develop an approach to the theory of relativistic geometric flows and emergent gravity defined by entropy functionals and related statistical thermodynamics models. Nonholonomic deformations of G.
Sergiu I. Vacaru   +2 more
doaj   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Cosmological solutions of a nonlocal square root gravity

open access: yesPhysics Letters B, 2019
In this paper we consider modification of general relativity extending R−2Λ by nonlocal term of the form R−2ΛF(□)R−2Λ, where F(□) is an analytic function of the d'Alembert operator □.
I. Dimitrijevic   +4 more
doaj   +1 more source

Causal Gödel-type metrics in non-local gravity theories

open access: yesEuropean Physical Journal C: Particles and Fields, 2021
It is well known that non-local theories of gravity have been a flourish arena of studies for many reasons, for instance, the UV incompleteness of General Relativity (GR). In this paper we check the consistency of ST-homogeneous Gödel-type metrics within
J. R. Nascimento   +2 more
doaj   +1 more source

On The Existence Of Anisotropic Cosmological Models In Higher-Order Theories Of Gravity

open access: yes, 2010
We investigate the behaviour on approach to the initial singularity in higher-order extensions of general relativity by finding exact cosmological solutions for a wide class of models in which the Lagrangian is allowed to depend nonlinearly upon the ...
Barrow J D   +13 more
core   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Inhomogeneous spacetimes in Weyl integrable geometry with matter source

open access: yesEuropean Physical Journal C: Particles and Fields, 2020
We investigate the existence of inhomogeneous exact solutions in Weyl Integrable theory with a matter source. In particular, we consider the existence of a dust fluid source while for the underlying geometry we assume a line element which belongs to the ...
Andronikos Paliathanasis   +2 more
doaj   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

Critical Phenomena in Gravitational Collapse

open access: yesLiving Reviews in Relativity, 2007
As first discovered by Choptuik, the black hole threshold in the space of initial data for general relativity shows both surprising structure and surprising simplicity.
Martín-García José M.   +1 more
doaj  

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