Results 111 to 120 of about 465,954 (329)

ERAD Component MoHrd3 Facilitates Pathogenicity and Establishes a Direct Regulation on Autophagy in Magnaporthe Oryzae

Advanced Science, EarlyView.
MoHrd3 plays a crucial role in regulating the pathogenicity of Magnaporthe oryzae. As an ER‐associated degradation component, MoHrd3 involves in ER stress‐triggered autophagy. It facilitates the fusion between the autophagosome and the vacuole via enhancing the interaction between MoAtg8 and MoYpt7.
Huiqing Xia, Yunna Zheng, Nan Yang, Jing Chen, Xi Wu, Ximing Zheng, Danrui Cui, Ruijin Wang, Xunli Lu, Dongli Wang, You‐liang Peng, Qian Chen   +11 more
wiley   +1 more source

Archaeological excavation : Skelhorne Street Phase 2, Liverpool [PDF]

, 2017
In April 2017, Salford Archaeology was commissioned by Nexus-Heritage to carry out an archaeological excavation of a well and potential workers housing at Skelhorne Street and Bolton Street, Liverpool (centred on NGR 335075 390430).
Mottershead, GD
core   +1 more source

EDTA‐Functionalized Nanoscale Metal–Organic Framework for Onco‐Cardiology via Radiochemotherapy Synergy and Spatiotemporally Matched Iron Chelation

Advanced Science, EarlyView.
Doxorubicin (DOX)‐induced cardiotoxicity is a major limitation to its broader clinical application, while cardioprotective interventions often risk reducing the anticancer efficacy of DOX. To address these challenges, this work constructs an EDTA‐functionalized metal–organic framework that enhances tumor therapy and provides efficient cardioprotection ...
Daojing Yuan, Liyang Tian, Luwen Zhuang, Yongyu Liang, Lingfei Chen, Xuetao Wang, Yanli Li, Xiyong Yu, Teng Gong   +8 more
wiley   +1 more source

Indoor Space Measurement with a Mobile Phone Integrated LIDAR Sensor: The Case of the Aizanoi Ancient City Zeus Temple Vaulted Gallery

Studies in Digital Heritage
While topographic measurement devices and methods continue to develop in earth sciences, some measurement tools have been adapted to consumer mobile devices.
Fikret Özbay, Yunus Çagrı Sarıkaya
doaj  

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

Advanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling, Aïda Yakhlef Sanchez, Nicolas Thelen, Müge Senarisoy, Maria Hogg, Steven Condamine, Andrea Lelli, Emilia Wysocka, Pranav Patni, Sandrine Vitry, Kerem Yasin Yildizhan, Sébastien Le Gal, Sylvie Nouaille, Michael R. Bowl, Marc Thiry, Didier Dulon, Sedigheh Delmaghani, Aziz El‐Amraoui   +17 more
wiley   +1 more source

Failure mechanism and early warning of an excavation-induced soil landslide

Frontiers in Earth Science
Due to the uncertainty in soil landslide failure mechanisms, lack of early warning systems for soil landslides and adoption of improper excavation configurations, soil landslides accidents triggered by highway excavation in Chinese mountainous areas ...
Yingfeng Wu, Demin Xue, Demin Xue, Demin Xue, Kai Chen, Cong Dai, Zhenyuan Hang, Zhongteng Wu, Zhongteng Wu, Shuai Zhang, Shuai Zhang   +10 more
doaj   +1 more source

An enhanced classification of artificial ground [PDF]

, 2010
This report describes a detailed scheme for the mapping and recording of artificial ground. It presents codes and descriptions that underpin the entries in the British Geological Survey stratigraphical ...
Cooper, A.H., Ford, J., Humpage, A.J., Kessler, H., Price, S.J.   +4 more
core  

m5C‐Modified tRF3b‐CysGCA‐23 Suppresses Bladder Cancer Malignancy by Repressing H3K18 Lactylation via Stabilizing RBM4

Advanced Science, EarlyView.
In this study, we identified an NSUN6‐dependent m5C‐modified tsRNA, m5C‐tRF3b CysGCA‐23 (mtRC), that is downregulated in BC and inversely correlated with disease progression. Mechanistically, mtRC suppresses BC malignancy by stabilizing RBM4, attenuating glycolysis, and thereby limiting H3K18 lactylation–mediated activation of IL1RAP and VASH2 ...
Xiaoling Ying, Yapeng Huang, Jian Huang, Qinyu Cai, Danni Zhang, Cong Chen, Yuxi Nie, Baotong Yang, Chuan Li, Wenyu Hu, Chang Xiong, Chengcheng Zhang, Ding Ji, Yaomin Liang, Mei Yang, Wenqi Wu, Weidong Ji   +16 more
wiley   +1 more source

Artificial ground freezing for underground construction – a brief review of the theory, practice and challenge

Frontiers in Built Environment
Since Artificial ground Freezing (AGF) appeared in the 1880s in the mining sector in Europe, it has been used for various construction applications worldwide.
Huan Mao, Jie Huang, Drew W. Johnson
doaj   +1 more source

Cars2‐Mediated Cysteine Catabolism Drives Brown Fat Development and Thermogenesis Through Persulfidating EBF2

Advanced Science, EarlyView.
We demonstrate that Cars2, a cysteine catabolic enzyme in mouse iBAT, is critical for cold tolerance and brown adipocyte differentiation. Through its CPERS activity, Cars2 produces CysSSH/H2S to induce EBF2 persulfidation, promoting its interaction with PPARγ and BRG1 to enhance thermogenic gene expression.
Xin Peng, Hongyong Song, Yin Long, Kaimin Wu, Yinkun Fu, Wenkai Zhou, Wenyan Li, Zhe Shi, Xu‐Yun Zhao   +8 more
wiley   +1 more source