Results 111 to 120 of about 339,132 (339)

Hepatic CBP/p300 Orchestrate Amino Acid‐Driven Gluconeogenesis through Histone Crotonylation

Advanced Science, EarlyView.
Hepatic CBP/p300 control amino acid‐driven gluconeogenesis by modulating histone crotonylation. This study identifies 2‐aminoadipate (2‐AAA) as a key metabolite that enhances crotonylation and activates amino acid and gluconeogenic gene expression.
Chunxiang Sheng, Tianjiao Li, Hong Lin, Xiaoqin Ma, Feiye Zhou, Mingzhu Li, Yiru Wang, Shushu Wang, Jialin Tan, Junmin Chen, Yulin Yang, Jianmin Liu, Yufang Bi, Jieli Lu, Xiao Wang, Libin Zhou   +15 more
wiley   +1 more source

Excavations in the Cambridgeshire Dykes [PDF]

The Antiquaries Journal, 1922
n ...
openaire   +2 more sources

Hepatic KLF9 Deficiency Inhibits Dehydroepiandrosterone (DHEA)‐Induced Polycystic Ovary Syndrome via Liver‐Ovary Axis

Advanced Science, EarlyView.
The study shows that liver is a previously unrecognized extraovarian organ that plays a key role about androgen homeostasis in the development of DHEA‐induced PCOS. DHEA is the most common precursor of active androgen, such as DHT, and KLF9 is required for the conversion of DHEA to DHT and hepatic KLF9 might be a potential therapeutic target for PCOS ...
Jianli Song, Zhaoqing Guan, Guiyi Ji, Jing Wang, Xiurui Yan, Yujie Zhang, Yinliang Zhang, Chunfang Ha, Rong Hu, Yongsheng Chang, Yaolin Zhang, Heng Fan   +11 more
wiley   +1 more source

Failure mechanism and early warning of an excavation-induced soil landslide

Frontiers in Earth Science
Due to the uncertainty in soil landslide failure mechanisms, lack of early warning systems for soil landslides and adoption of improper excavation configurations, soil landslides accidents triggered by highway excavation in Chinese mountainous areas ...
Yingfeng Wu, Demin Xue, Demin Xue, Demin Xue, Kai Chen, Cong Dai, Zhenyuan Hang, Zhongteng Wu, Zhongteng Wu, Shuai Zhang, Shuai Zhang   +10 more
doaj   +1 more source

Excavations at Gellygaer [PDF]

The Classical Review, 1910
n ...
openaire   +2 more sources

Fault slip in a mining context [PDF]

, 2004
Recent articles on the broad range of computational and analytic techniques currently used to investigate excavation collapse are reported. Advances in physical models are also described.
Fowkes, N.D., Mason, D.P., Napier, J.A.L.   +2 more
core  

Active Learning‐Assisted Exploration of [PO40Mo12]3− for Alzheimer's Therapy Insights

Advanced Science, EarlyView.
Bayesian Optimization coupled with active learning to uncover the interaction mechanism of [PO40Mo12]3− on amyloid‐β peptide. Abstract Alzheimer's disease (AD), involving amyloid‐β (Aβ) aggregation, has potential therapeutic modulators in polyoxometalates (POMs) like [PMo12O40]3−.
Lincan Fang, Ruoxue Peng, Luping Xia, Gui‐lin Zhuang   +3 more
wiley   +1 more source

Indoor Space Measurement with a Mobile Phone Integrated LIDAR Sensor: The Case of the Aizanoi Ancient City Zeus Temple Vaulted Gallery

Studies in Digital Heritage
While topographic measurement devices and methods continue to develop in earth sciences, some measurement tools have been adapted to consumer mobile devices.
Fikret Özbay, Yunus Çagrı Sarıkaya
doaj  

Artificial ground freezing for underground construction – a brief review of the theory, practice and challenge

Frontiers in Built Environment
Since Artificial ground Freezing (AGF) appeared in the 1880s in the mining sector in Europe, it has been used for various construction applications worldwide.
Huan Mao, Jie Huang, Drew W. Johnson
doaj   +1 more source

The Harvard Expedition to Samaria: Excavations of 1909 [PDF]

, 1910
George Andrew Reisner
openalex   +1 more source