Results 41 to 50 of about 689,888 (317)

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

open access: yesFEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

Effect of temperature and time after collection on buck sperm quality

open access: yesBMC Veterinary Research, 2019
Background Different parameters are assessed as part of the semen analysis but a standard protocol for evaluation of goat semen is still missing.
Kirsten Hahn   +2 more
doaj   +1 more source

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

open access: yesFEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke   +2 more
wiley   +1 more source

Precise Modelling of Compensating Business Transactions and its Application to BPEL

open access: yes, 2005
We describe the StAC language which can be used to specify the orchestration of activities in long running business transactions. Long running business transactions use compensation to cope with exceptions. StAC supports sequential and parallel behaviour
Butler, Michael   +2 more
core   +4 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Exception Handling in Programmable Controllers with Denotational Model [PDF]

open access: yesAnnals of computer science and information systems, 2023
Jan Sadolewski, Bartosz Trybus
doaj   +1 more source

The Energy-Aware Multi-UAV Dispatch and Handoff Algorithm for Maximizing the Event Communication Time in Disasters

open access: yesApplied Sciences, 2021
For handling the broken-down communication infrastructure when a disaster event happens, this paper proposes to dispatch the unmanned aerial vehicle (UAV) to the disaster area as the relay node, which further forms a Flying Ad hoc Network (FANET).
Ing-Chau Chang   +2 more
doaj   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Label algebras and exception handling

open access: yesScience of Computer Programming, 1994
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Marc Aiguier   +2 more
openaire   +3 more sources

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