Results 161 to 170 of about 15,532,780 (319)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Indicators and Bacterial Diversity of Subclinical Mastitis in Iran's Industrial Cattle Farms. [PDF]

Vet Med Sci
Kalantari R, Salajegheh Tazerji S, Garaei N.   +2 more
europepmc   +1 more source

Radical subgroups of the finite exceptional groups of Lie type E6

, 2014
J. An, H. Dietrich, Shih-Chang Huang
semanticscholar   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Variability in Standardized Letters of Evaluation: A Multi-Institutional Review of EM Residency Based Versus Non-Residency Based Faculty Evaluation. [PDF]

AEM Educ Train
Gore K, Hegarty CB, Beardsley T, Krzyzaniak SM, Monteiro S, Alvarez A, Davis T, Parsons M, Pandey A, Bord S, Gottlieb M, Mannix A.   +11 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Triplet Excitons Unlock Electroluminescence from Insulating Lanthanide Nanocrystals for Light-Emitting Diode Applications. [PDF]

Research (Wash D C)
Li W, Lian W, Tu D.
europepmc   +1 more source

Visible actions on flag varieties of exceptional groups and a generalization of the Cartan decomposition

, 2014
Yu-ichi Tanaka
semanticscholar   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

WDR12 and HIVEP3 are contributors to cognitive preservation in Amish SuperAgers. [PDF]

Alzheimers Dement
Dorfsman D, Prough MB, Gulyayev A, Caywood LJ, Clouse JE, Herington SD, Slifer SH, Adams LD, Laux RA, Song YE, Lynn A, Fuzzell SL, Hochstetler SD, Miskimen K, Main LR, Wang P, Liu Y, Moore N, Ogrocki P, Lerner AJ, Vance JM, Cuccaro ML, Haines JL, Pericak-Vance MA, Scott WK.   +24 more
europepmc   +1 more source