Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Birefringent crystal materials used for modulating light polarization are of great significance in optical communication applications. According to the numerous reported organic–inorganic hybrid optical crystal materials, adopting π‐conjugated groups ...
Ru‐Ling Tang +4 more
doaj +1 more source
An Investigation into the Relationship between Attachment to God and Mental Health in the Parents of Exceptional and Normal Children in Hamedan City in the Academic Year 2008–2009 [PDF]
Objective: This study aims at investigating the relation between attachment to God and mental health among the parents of exceptional and normal children. Method: The present study is an applied research conducted by correlational methodology.
Amin Hasanpour +3 more
doaj
We describe simply connected compact exceptional simple Lie groups in very elementary way. We first construct all simply connected compact exceptional Lie groups G concretely. Next, we find all involutive automorphisms of G, and determine the group structures of the fixed points subgroup. They correspond to the classification of all irreducible compact
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Exceptional epidemics: AIDS still deserves a global response
There has been a renewed debate over whether AIDS deserves an exceptional response. We argue that as AIDS is having differentiated impacts depending on the scale of the epidemic, and population groups impacted, and so responses must be tailored ...
Smith Julia, Whiteside Alan
doaj +1 more source
Exceptional groups from open strings [PDF]
25 pages, LATEX, 9 figures; minor changes, two references ...
Gaberdiel, M. R., Zwiebach, B.
openaire +2 more sources
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Examining influences of neuromuscular block post tetanic monitoring technique on the quality of surgical conditions: Neuromuscular block and quality of surgical conditions [PDF]
Introduction: Subjective estimation of neuromuscular block (NMB), focused on clinical signs such as visual and tactile estimation, can be very difficult and conducted only on awake patients. Hence, it seems that usage of NMB's objective monitoring should
Janković Radmilo +5 more
doaj +1 more source

