Results 101 to 110 of about 7,457,680 (317)

Spatial counterfactuals to explore disastrous flooding

open access: yesEnvironmental Research Letters
Flood-prone people and decision-makers are often unwilling to discuss and prepare for exceptional events, as such events are hard to perceive and out of experience for most people. Once an exceptional flood occurs, affected people and decision-makers are
Bruno Merz   +8 more
doaj   +1 more source

The questions of the operation of law in time while overcoming the gaps in legislation

open access: yesТеорія і практика правознавства, 2016
The article analyses the ways of retention of the time parameters set for a particular legal norm while application of the latter for overcoming the gaps in legislation.
О. В. Пушняк
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Thematic linking in Hausa asymmetric coordination

open access: yesStudies in African Linguistics, 1989
This paper investigates "asymmetric coordination" in Nigerian Hausa. A range of constructions is presented in which asymmetric coordination occurs, and their syntactic and semantic properties are established.
Linda Schwartz
doaj   +3 more sources

Infinite and finite consistent truncations on deformed generalised parallelisations

open access: yesJournal of High Energy Physics
Given a manifold M $$ \mathbbm{M} $$ admitting a maximally supersymmetric consistent truncation, we show how to formulate new consistent truncations by restricting to a set of Kaluza-Klein modes on M $$ \mathbbm{M} $$ invariant under some subgroup of the
Chris D. A. Blair   +2 more
doaj   +1 more source

Counting sums of exceptional units in $ \mathbb{Z}_n $

open access: yesAIMS Mathematics
Let $ R $ be a commutative ring with the identity $ 1_{R} $, and let $ R^* $ be the multiplicative group of units in $ R $. An element $ a\in R^* $ is called an exceptional unit if there exists a $ b\in R^* $ such that $ a+b = 1_{R} $.
Junyong Zhao
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Hölder Quasicontinuity in Variable Exponent Sobolev Spaces

open access: yesJournal of Inequalities and Applications, 2007
We show that a function in the variable exponent Sobolev spaces coincides with a Hölder continuous Sobolev function outside a small exceptional set.
Kinnunen Juha   +2 more
doaj  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Deforming nonnormal isolated surface singularities and constructing 3-folds with $\mathbb{P}^1$ as exceptional set

open access: yes, 2015
Normally one assumes isolated surface singularities to be normal. The purpose of this paper is to show that it can be useful to look at nonnormal singularities.
Stevens, Jan
core  

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