Results 91 to 100 of about 1,610,927 (333)

Excess Body Weight and Gastroesophageal Reflux Disease [PDF]

, 2021
Andreas Thalheimer, Marco Bueter
openalex   +1 more source

Short-term outcomes of laparoscopic gastric plication in morbidly obese patients: Importance of postoperative follow-up [PDF]

, 2013
Demand for feasible, safe, and preferably low-cost methods of weight reduction is rising every day. The present study reports findings from laparoscopic gastric plication (LGP), which is a new restrictive bariatric technique, combined with a ...
Maleki, A.R., Niazi, M., Talebpour, M.
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

THE IMPACT OF AUTHORIZATION IN THE ASSESSMENT OF RISKS AND SAFETY MEASURES OF OVERSIZED TRANSPORT ACTIVITY

Journal of Social Sciences
The article aims to analyze the regulations and regulatory framework regarding the authorization of oversized transport, highlighting their importance in ensuring road safety and protecting the infrastructure.
GARSTEA, Nina
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Less underestimaton of excess weight by the categorical than the visual method. Its determinants and feeding practices in Mexican mothers of children aged 2 to 12 years

, 2023
Yolanda Flores-Peña, Ana María Salinas‐Martínez, Perla María Trejo Ortiz, Hermelinda Áviila Alpirez, Josefina Gallegos-Martínez, Alicia Ugarte-Esquivel   +5 more
openalex   +1 more source

NUTRITION AND THE ECONOMICS OF SWINE MANAGEMENT [PDF]

Current methods of formulating animal rations lead to excess nutrient excretion which can potentially lead to excess manure nutrients and an increase in economic costs. These methods do not recognize the impact of diminishing returns. The objective is to
Boland, Michael A., Foster, Kenneth A., Preckel, Paul V.   +2 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Transonic off-design drag and performance of three mixed-compression axisymmetric inlets [PDF]

An experimental investigation was conducted to determine the off-design drag and pressure performance of three axisymmetric supersonic inlets in the transonic speed range.
Choby, D. A., Meleason, E. T., Woollett, R. R.   +2 more
core   +1 more source

Mechanics of large folds in thin interfacial films

, 2014
A thin film at a liquid interface responds to uniaxial confinement by wrinkling and then by folding; its shape and energy have been computed exactly before self contact. Here, we address the mechanics of large folds, i.e.
Davidovitch, Benny, Démery, Vincent, Santangelo, Christian D.   +2 more
core   +1 more source