Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
We performed a large-scale micromagnetics simulation on a supercomputing system to investigate the properties of isotropic nanocrystalline permanent magnets consisting of cubic grains.
Hiroshi Tsukahara +4 more
doaj +1 more source
Non-Hermitian indirect exchange interaction in a topological insulator coupled to a ferromagnetic metal. [PDF]
Hosseini MV, Askari M.
europepmc +1 more source
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin +11 more
wiley +1 more source
Self-consistent solution for the magnetic exchange interaction mediated by a superconductor. [PDF]
Ghanbari A, Risinggård VK, Linder J.
europepmc +1 more source
Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein +13 more
wiley +1 more source
Spinning Molecules, Spinning Spins: Modulation of an Electron Spin Exchange Interaction in a Highly Anisotropic Hyperfine Field. [PDF]
Brugh AM +3 more
europepmc +1 more source
Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source
Indirect Exchange Interaction Fields in Magnetic Nanogranular Films [PDF]
The investigation results of the influence of non-magnetic matrix conducting properties on the magnetization process of magnetic nanogranular films are presented.
Yu.I. Dzhezherya +4 more
doaj
Observation of Yu-Shiba-Rusinov States and Inelastic Tunneling Spectroscopy for Intramolecule Magnetic Exchange Interaction Energy of Terbium Phthalocyanine (TbPc) Species Adsorbed on Superconductor NbSe2. [PDF]
Shahed SMF +5 more
europepmc +1 more source

