Results 51 to 60 of about 176,931,771 (275)

Design and Implementation of the ZH/EN Bilingual Retrieval System Based on the CAT/AGROVOC Mapping

Journal of Integrative Agriculture, 2012
For the users' convenience of accessing the AGRIS resources quickly and using them fully, the paper decomposes the structure of AGRIS Search net, analyzes the users' requirement met for conducting a bilingual (ZH/EN) retrieval, the system function ...
Wei SUN, Xue-fu ZHANG, Ahsan Morshed, Gudrun Johannsen, Johannes Keizer, Yves Jaques, Stefano Anibald, Nan LI, Jia-yi LIU   +8 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Multi-source Data Acquisition and Comprehensive Evaluation System for Intelligent Business District [PDF]

Jisuanji gongcheng, 2019
Focusing on the data requirement of intelligent business district’s construction,this paper designs a multi-source data acquisition and comprehensive evaluation system.The system uses the Pyspider framework to collect data.Based on the idea of dichotomy ...
WANG Jiahui,GUO Yi,WEN Xinxiu,WAN Feng
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Exchange of medicinal plant information in California missions [PDF]

, 2020
Background Missions were established in California in the eighteenth and nineteenth centuries to convert Native Americans to Christianity and enculturate them into a class of laborers for Californios (Spanish/Mexican settler).
McBride, Deborah Lea, Calvo, María Isabel, Cavero, Rita Yolanda, McBride, J.R. (Joe Rayl), McBride, D.L. (Deborah Lea), McBride, Joe Rayl, Cavero-Remon, R.Y. (Rita Yolanda), Cheshire, A.L. (Anna Liisa), Cheshire, Anna Liisa, Calvo, M.I. (María Isabel), Anna Liisa Cheshire, Deborah Lea, Rita Yolanda Cavero, Joe Rayl McBride, María Isabel Calvo   +14 more
core   +1 more source

PRAM: A Novel Approach for Predicting Riskless State of Commodity Future Arbitrages With Machine Learning Techniques

IEEE Access, 2019
Arbitrage risk management is a very hot and challengeable topic in the commodity future market. To resist the possible risk of an arbitrage, exchanges have to withdraw margin from clients referring to the case of maximum risk.
Feng He, Yan-Dong Wen
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Exchange of Information and Evidence between Competition Authorities and Entrepreneurs’ Rights [PDF]

Yearbook of Antitrust and Regulatory Studies, 2012
This article concentrates on the exchange of information and evidence between competition authorities. The issue is analyzed from the perspective of both antitrust and merger cases.
Mateusz Błachucki, Sonia Jóźwiak
doaj