Results 201 to 210 of about 21,346,999 (262)

Single‐Particle FRET Probes Heterogeneity in the Ligand Shell of Colloidal Perovskite Quantum Dots

open access: yesAdvanced Materials, EarlyView.
Single‐particle, single‐molecule Förster resonance energy transfer turns dye‐tagged ligands into nanorulers for the otherwise elusive organic shell of CsPbBr3 quantum dots. Distance variations within individual particles reveal pronounced local heterogeneity, while changes in the surrounding ligand chemistry shift the average dye–surface separation ...
Leon G. Feld   +6 more
wiley   +1 more source

Microgels Enable iPSCs to Assemble, Expand, and Differentiate Into Organoids—From Sizable to High‐Throughput

open access: yesAdvanced Materials, EarlyView.
A chemically defined PEG‐based microgel platform enables scalable, reproducible production of three‐dimensional microgel‐iPSC constructs in multiple sizes. The system is compatible with high‐throughput automation and supports human iPSC expansion and differentiation within a single construct, including directed differentiation into cardiac organoids ...
Laura Klasen   +8 more
wiley   +1 more source

Programmable Carrier‐Free All‐Enzyme Beads for Modular Continuous‐Flow Biocatalysis

open access: yesAdvanced Materials, EarlyView.
Genetically encoded enzyme building blocks self‐assemble into monodisperse, carrier‐free protein beads via a droplet‐based formulation strategy. These programmable catalytic particles enable modular continuous‐flow biocatalysis, from single‐enzyme reactions to multi‐enzyme cascades and bead–bead coupled reactor systems.
Jennifer Kühne   +12 more
wiley   +1 more source

Seamless Mechanical Programming Through Hybrid Epoxy–Acrylate Printing for Soft–Rigid Robots

open access: yesAdvanced Materials, EarlyView.
Hybrid epoxy‐acrylate printing enables seamless fabrication of soft–rigid robotic systems with covalently integrated interfaces and functionally graded mechanics. Grayscale exposure expands the accessible material space, enabling spatially programmed actuation through patterned stiffness while revealing the mechanics and durability of continuously ...
David C. Bershadsky   +3 more
wiley   +1 more source

Increasing Lipid Nanoparticle mRNA Copy Number Improves Transfection Potency

open access: yesAdvanced Materials, EarlyView.
As lipid nanoparticle (LNP) systems are the leading platform for in vivo nucleic acid delivery, improving transfection potency of these systems is of considerable interest. In this work, we explored a post‐mixing formulation method involving a two‐step buffer exchange that increased the number of mRNA copies within each LNP while reducing the number of
Yao Zhang   +12 more
wiley   +1 more source

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