Results 41 to 50 of about 923,758 (324)
FEBS Open Bio, EarlyView.The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik +3 more
wiley +1 more source
Modelling cytoskeletal traffic: an interplay between passive diffusion and active transport [PDF]
Phys. Rev. Lett. 110, 098102 (2013), 2012 We introduce the totally asymmetric exclusion process with Langmuir kinetics (TASEP-LK) on a network as a microscopic model for active motor protein transport on the cytoskeleton, immersed in the diffusive cytoplasm. We discuss how the interplay between active transport along a network and infinite diffusion in a bulk reservoir leads to a heterogeneous
arxiv +1 more source
FEBS Open Bio, EarlyView.SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel +13 more
wiley +1 more source
FEBS Open Bio, EarlyView.Ca2+‐mediated response to DMSO was investigated in Saccharomyces cerevisiae cells expressing Ca2+‐dependent aequorin. Cell exposure to DMSO induced a cytosolic Ca2+ wave dependent on the integrity of the Cch1/Mid1 channel. Deletion of KCS1 or VIP1 genes encoding the phosphoinositol pyrophosphate (PP‐IP) synthases suppressed the DMSO‐induced Ca2 ...
Larisa Ioana Gogianu +4 more
wiley +1 more source
Thermal Atom-Ion Collisions in K-Yb$^{+}$ Hybrid System [PDF]
Phys. Rev. A 100, 022701 (2019), 2019 We present experimental studies of atom-ion collisions using buffer-gas cooled, trapped ytterbium (Yb$^+$) ions immersed in potassium (K) vapor. The range of the collisional temperature is on the order of several hundred kelvin (thermal regime). We have determined various collisional rate coefficients of the Yb$^+$ ion per K-atom number density.
arxiv +1 more source
Annals of Clinical and Translational Neurology, EarlyView.Abstract Objectives Intravenous immunoglobulin (IVIg) is an effective treatment for Guillain–Barré syndrome (GBS), but recovery varies between patients. This study aims to evaluate the pharmacokinetics (PK) and pharmacodynamics (PD) of a single and a second IVIg dose (SID) in patients with GBS.
Sander J. van Tilburg +7 more
wiley +1 more source
Quantum suppression of cold reactions far from the s-wave energy limit [PDF]
arXiv, 2022 Reactions between pairs of atoms are ubiquitous processes in chemistry and physics. Quantum scattering effects on reactions often require extremely ultracold temperatures, approaching the $s$-wave regime, with a small number of partial waves involved.
arxiv
Arthritis Care &Research, EarlyView.Objective The increasing burden associated with low back pain (LBP) is a critical issue. This is a novel analysis of trends in risk factors for LBP aiming to identify risk factors that require further attention or consideration in global policies to reduce the burden of LBP.
Katharine E. Roberts +5 more
wiley +1 more source
The Duration of Fixed Exchange Rate Regimes [PDF]
SSRN Electronic Journal, 2005 This paper studies the survival of fixed exchange rate regimes. The probability of an exit from a fixed exchange rate regime depends on the time spent within this regime. In such a context durations models are appropriate, in particular because of the possible non-monotonic pattern of duration dependence.
openaire +3 more sources
Mucus Physically Restricts Influenza A Viral Particle Access to the Epithelium
Advanced Biology, EarlyView.The infectious potential of respiratory viruses depends on their ability to navigate through a layer of mucus that serves as a protective barrier in the lung. It is demonstrated that influenza A virus penetration through mucus is significantly limited by the gel's internal microstructure and, to a lesser extent, by adhesive binding to mucin glycans ...
Logan Kaler +8 more
wiley +1 more source