Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans +7 more
wiley +1 more source
The Interest Rate-Exchange Rate Link in the Mexican Float [PDF]
This paper examines empirically the interest rate-exchange rate link in the context of the Mexican experience with a floating exchange regime. The impulse response function derived from an ECM estimated by GMM reveals a lasting positive effect of a ...
Carlos A. Ibarra
core
A Personalized, Rate-of-Rise (ROR)-Driven Model to Optimize Red Cell Exchange Interval in Chronic Sickle Cell Management. [PDF]
Nadim M, Choi A, Parisi N, Akgun Y.
europepmc +1 more source
Silicone breast implants are presented as a model system for understanding polymer permeation in vivo. Rather than representing material failure, “gel bleed” emerges from solution–diffusion transport‐mediated. By integrating polymer architecture, physicochemical transport, and biointerfacial processes, this review provides a unified framework that ...
D. Bouyer +12 more
wiley +1 more source
Does Exchange Rate Risk Matter for Welfare? [PDF]
Volatility in exchange rates is a prominent feature of open economies, a fact which has motivated elaborate attempts in many countries at exchange rate management.
Paul R. Bergin, Ivan Tchakarov
core
Early Exchange Transfusion in Critical Pertussis: A Case Report Supporting Timely Intervention. [PDF]
Al-Hashemi E, Shalaby O, Altammar F.
europepmc +1 more source
Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu +4 more
wiley +1 more source
Risk premium shocks, monetary policy and exchange rate pass-through in small, open countries [PDF]
The central banks of small, open countries often face the problem that the exchange rate of their currency appreciates or depreciates in response to impacts of external origin.
Balázs Vonnák
core
Mobilidade de capital internacional no Brasil
Marcos Costa Holanda +1 more
doaj
Real-world evidence of water exchange colonoscopy improving adenoma detection rates: A propensity score-matched analysis. [PDF]
Chao YJ +6 more
europepmc +1 more source

