Results 91 to 100 of about 5,020,077 (309)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Bubbling and crashing exchange rates. [PDF]

open access: yes
Exchange; Exchange rates; Working;
Grimaldi, Maria, De Grauwe, Paul
core  

On the congruence of exchange rates under a system of bilateral trade

open access: yesPSL Quarterly Review, 2014
The article makes a contribution to the problem recently raised, by Prof. Bresciani-Turroni and Prof. Gini, about the concordance of direct exchange rates and cross-rates under a system of bilateral trade.
G. D’IPPOLITO
doaj   +1 more source

Forward Exchange Rates as Estimates of Exchange Rate Expectations: A Comment [PDF]

open access: yesInternational Finance Discussion Papers, 1972
In a recent note Jeremy Siegel applied the statisitcal theorem -- that the expectation of a positive random variable with positive variance will be greater than the reciprocal of the expectation of the inverse of the random variable -- to demonstrate that "[e]ven in the simple case where investors are risk-neutral, ..., it can be shown that the forward
openaire   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

CAN EXCHANGE RATES FORECAST COMMODITY PRICES? [PDF]

open access: yes
This paper studies the dynamic relationship between exchange rate fluctuations and world commodity price movements. Taking into account parameter instability, we demonstrate surprisingly robust evidence that exchange rates predict world commodity price ...
Rossi, Barbara   +2 more
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Explaining Real Exchange Rates Fluctuations [PDF]

open access: yes
This paper attempts to explain the sources of real exchange rate fluctuations for a set of advanced economies and Central and Eastern European transition economies.
Amalia Morales Zumaquero.
core  

On the congruence of exchange rates under a system of bilateral trade. A reply

open access: yesPSL Quarterly Review, 2014
A reply to Dr. Gioacchino d’Ippolito’s article on the problem of the concordance of direct exchange rates and cross-rates under a system of bilateral trade.
C. BRESCIANI-TURRONI
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

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