Results 41 to 50 of about 455,456 (309)

Idiosyncratic risk Pricing: Evidence from Tehran Stock Exchange [PDF]

open access: yesمطالعات تجربی حسابداری مالی, 2015
The purpose of this research is the empirical test of idiosyncratic risk pricing in Tehran Stock Exchange during 1378 to 1389. The research is considered as “Ex-post facto” that has been done using “portfolio study approach” and is based on observational
Mohammad Arabmazar Yazdi   +2 more
doaj   +3 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Exchange Rate Risk On The Mortgage Market

open access: yesReal Estate Management and Valuation, 2015
Strict connections of the real estate market with the financial market are an unquestionable phenomenon at every level of investing, starting from the lowest individual investor, and finishing with national and transnational players.
Siemińska Ewa, Krajewska Małgorzata
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

EVALUACIÓN DEL MERCADO DE OPCIONES SOBRE TASAS DE CAMBIO: PERSPECTIVAS PARA UNA MEJOR UTILIZACIÓN

open access: yesRevista EIA, 2007
Colombia debe contar con un mercado financiero acorde con las necesidades de la internacionaliza-ción de su economía. Para esto requiere desarrollar un mercado de derivados, y entre ellos el de opciones sobre la tasa de cambio peso/dólar, de modo que se ...
Iván Darío Ochoa, Cristina González
doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Interest exchange: Tool for risk management

open access: yesTạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kinh tế và Quản trị kinh doanh, 2020
Giao dịch hoán đổi lãi suất là việc các bên giao kết hợp đồng với nhau, theo đó mỗi bên cam kết thanh toán cho bên kia khoản tiền lãi tính theo lãi suất thả nổi hay lãi suất cố định trên cùng một khoản nợ gốc trong cùng một khoảng thời gian. Hoán đổi lãi
Nguyễn Minh Kiều
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Exchange rates, macroeconomic fundamentals and risk aversion

open access: yes, 2014
This paper proposes a theoretical model for determining the exchange rate based on the interaction between international bond markets with different maturities. The model accommodates the presence of risk premia between short- and long-term bonds.
Laborda, R., Olmo, J.
core   +1 more source

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