Results 41 to 50 of about 6,382 (263)
On the size of the block of 1 for
Modern Stochastics: Theory and Applications, 2017 We study the frequency process $f_{1}$ of the block of 1 for a Ξ-coalescent Π with dust. If Π stays infinite, $f_{1}$ is a jump-hold process which can be expressed as a sum of broken parts from a stick-breaking procedure with uncorrelated, but in general
Fabian Freund, Martin Möhle
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Convergence to the coalescent and its relation to the time back to the most recent common ancestor [PDF]
Discrete Mathematics & Theoretical Computer Science, 2008 For the class of haploid exchangeable population models with non-overlapping generations and population size $N$ it is shown that, as $N$ tends to infinity, convergence of the time-scaled ancestral process to Kingman's coalescent and convergence in ...
Martin Möhle
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FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Strong laws of large numbers for arrays of row-wise exchangeable random elements
International Journal of Mathematics and Mathematical Sciences, 1985 Let {Xnk,1≤k≤n,n≤1} be a triangular array of row-wise exchangeable random elements in a separable Banach space.
Robert Lee Taylor +1 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Relational exchangeability [PDF]
Journal of Applied Probability, 2019 AbstractA relationally exchangeable structure is a random combinatorial structure whose law is invariant with respect to relabeling its relations, as opposed to its elements. Historically, exchangeable random set partitions have been the best known examples of relationally exchangeable structures, but the concept now arises more broadly when modeling ...
Harry Crane, Walter Dempsey
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
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