Results 81 to 90 of about 10,338 (302)

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Comparisons Between Frequency Distributions Based on Gini’s Approach: Principal Component Analysis Addressed to Time Series

open access: yesEconometrics
In this paper, time series of length T are seen as frequency distributions. Each distribution is defined with respect to a statistical variable having T observed values.
Pierpaolo Angelini
doaj   +1 more source

The principle of signature exchangeability [PDF]

open access: yes, 2015
We investigate the notion of a signature in Polyadic Inductive Logic and study the probability functions satisfying the Principle of Signature Exchangeability.
Vencovska, Alena, Ronel, Tahel
core   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

When Should Demographics Enter the Prior? Conditional Exchangeability in Bayesian Estimation of Risk Preferences

open access: yesRisks
Hierarchical Bayesian models for the estimation of individual risk preferences typically assume that subjects are unconditionally exchangeable: prior to seeing any data, every subject is treated as a draw from a common population distribution. We examine
Xiaoxue Sherry Gao, Glenn W. Harrison
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Tractability through exchangeability: A new perspective on efficient probabilistic inference [PDF]

open access: yes, 2014
Exchangeability is a central notion in statistics and probability theory. The assumption that an infinite sequence of data points is exchangeable is at the core of Bayesian statistics.
Niepert, Mathias, Van den Broeck, Guy
core  

Asymptotic supervised predictive classifiers under partition exchangeability

open access: yes, 2021
In inductive inference phenomena from the past are modeled in order to make predictions of the future. The mathematical concept of exchangeability for random sequences provides a mathematical justification for the assumption that observations are ...
Kinnula, Ville
core  

Home - About - Disclaimer - Privacy