Results 61 to 70 of about 2,982,530 (319)

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

La frontière indienne du Río de la Plata, un espace de contact et d'échanges

open access: yesAmerika, 2010
Marginal area of the Hispanic colonization, the Río de la Plata did not follow the general scheme of the Conquest, with an Indian Frontier beyond which the Natives remained free and with effective control of their territory. The History of this region is
Ghislaine Dagorn
doaj   +1 more source

Multi-State Health Insurance Exchanges [PDF]

open access: yes, 2011
Considers possible advantages of creating multi-state exchanges: administrative economies of scale, ability to serve multi-state metropolitan areas, pooling across state lines, and a critical mass of insured persons to establish stable risk ...
Linda J. Blumberg
core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Overview of Final Exchange Regulations [PDF]

open access: yes, 2012
Summarizes rules and regulations for establishing and operating state health insurance exchanges, as well as implications for eligibility determinations, verification rules, qualified health plans, and user fees and financial support for ...

core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Health Insurance Exchanges: Health Insurance “Navigators” and In-Person Assistance [PDF]

open access: yes, 2013
The 2010 Patient Protection and Affordable Care Act (ACA, P.L. 111-148) allows certain individuals and small businesses to buy health insurance through state exchanges, beginning on October 1, 2013.
Kirchhoff, Suzanne M
core   +3 more sources

Structure of the nuclear force in a chiral quark-diquark model

open access: yes, 2003
We discuss the structure of the nuclear force using a lagrangian derived from hadronization of a chiral quark and diquark model. A generalized trace log formula including meson and nucleon fields is expanded to the order in which relevant terms emerge ...
Hosaka, A., Nagata, K.
core   +2 more sources

Paired and altruistic kidney donation in the UK: Algorithms and experimentation [PDF]

open access: yes, 2014
We study the computational problem of identifying optimal sets of kidney exchanges in the UK. We show how to expand an integer programming-based formulation due to Roth et al.
Manlove, David, O'Malley, Gregg
core   +1 more source

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