Results 81 to 90 of about 2,982,530 (319)

Overcoming financing constraints to corporate expansion: evidence from a company in an emerging Islamic market [PDF]

open access: yes, 2009
The sourcing of low-cost finance to facilitate corporate expansion on competitive terms is a major challenge to firms from emerging markets. There are additional constraints in Islamic markets as financial instruments must adhere to shari’ya law.
Hearn, Bruce   +2 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Governance Issues for Health Insurance Exchanges [PDF]

open access: yes, 2011
Outlines considerations for states in deciding how to structure a health insurance exchange, as well as issues of funding sources, operational flexibility, political independence and accountability, management structure, and sub-state ...
Paul N. Van de Water, Richard P. Nathan
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Regularization method for parabolic equation with variable operator

open access: yesJournal of Applied Mathematics, 2005
Consider the initial boundary value problem for the equation ut=−L(t)u, u(1)=w on an interval [0,1] for t>0, where w(x) is a given function in L2(Ω) and Ω is a bounded domain in ℝn with a smooth boundary ∂Ω.
Valentina Burmistrova
doaj   +1 more source

THE LEGAL PROBLEMS OF INFORMATION EXCHANGE IN SYSTEM OF TAX AUTHORITIES

open access: yesПравоприменение, 2018
The subject. The article is devoted to legal issues in the regulation of relations on information exchange between departments of the Federal Tax Service of Russia and their officials.The purpose of the article is to determine the legal basis, allowing ...
K. Maslov
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Marseille et la Gaule méditerranéenne avant la conquête romaine

open access: yesPallas, 2009
Ever since the end of the VIIth century B.C., Marseilles represents a major if not unique stage in the relations between the Mediterranean and inland Gaul.
Sophie Collin Bouffier
doaj   +1 more source

Purpose and potential for commodity exchanges in African economies: [PDF]

open access: yes
This paper reviews the purpose and potential of commodity exchanges in Africa. Drawing from the existing literature and using indicative empirics, it examines the conditions that enable successful exchanges, highlights the special challenges to setting ...
Garcia, Philip   +2 more
core  

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