ABSTRACT Osteoarthritis (OA) remains without disease‐modifying sssstherapies, in part due to biological heterogeneity and a hostile joint microenvironment that undermines one‐size‐fits‐all interventions. Extracellular vesicles (EVs) play a dual role in OA pathophysiology: endogenous EVs disseminate pro‐inflammatory and catabolic signals that propagate ...
Duc‐Hiep Bach +2 more
wiley +1 more source
Development of Spray-Dried Mannitol-Pregelatinized Rice Starch Using SeDeM-Based Approach for Direct Compressible Cetirizine Dihydrochloride Tablets. [PDF]
Saokham P +4 more
europepmc +1 more source
A sustainable reversed‐phase liquid chromatography method is developed for diltiazem analysis and pKadetermination. The study integrates green and white analytical chemistry frameworks to evaluate environmental impact and practicality. The Environmental, Performance, and Practicality Index is utilized as a comprehensive, holistic tool for the ...
Zehra Üstün +2 more
wiley +1 more source
Assessing the Impact of Mesoporous, Co-Amorphous, and Polymer-Based Systems on Cefdinir's Dissolution and Stability Via Predictive Modeling. [PDF]
Al Nuss R, Al Tahan MA, El-Zein H.
europepmc +1 more source
<strong>The role of excipients in neglected tropical diseases</strong>
Dolores Serrano +2 more
openalex +2 more sources
Eco‐Friendly Preparation of Porous Starch via Water‐Induced Amylose Solubilization
ABSTRACT Starch is a safe and biocompatible excipient in pharmaceutical formulations. Introducing pores into its granules transforms it into a biodegradable carrier suitable for drug delivery. Various strategies have been developed to induce pore formation, including physical methods (e.g., microwave, ultrasound), chemical methods (e.g., solvent ...
Anna Imbriano +9 more
wiley +1 more source
Solvent-free aqueous spray drying of poorly soluble drugs enabled by hot-feed micellar solubilization and high-Tg polymer matrices. [PDF]
Zheng W +5 more
europepmc +1 more source
Surfactant-Particle Engineering Hybrids: Emerging Strategies for Enhancing Solubility and Oral Bioavailability of Poorly Water-Soluble Drugs. [PDF]
Kim KS, Cho HJ, Din FU, Cho JH, Choi HG.
europepmc +1 more source
Advanced Chemical and Imaging Methods for Studying Structure Morphology and Excipients Solid State Transformations in Pharmaceutical Multiparticulate Formulations [PDF]
Elizabeth J. Legge +9 more
openalex +1 more source

