ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Photoluminescence Emitter with 100% Power Efficiency─The Key Role of the Absorption Edge in CsPbBr<sub>3</sub> Perovskite Quantum Dots. [PDF]
Valenta J, Greben M, Takagi T, Vacha M.
europepmc +1 more source
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos +2 more
wiley +1 more source
Relation between Structure and Functionality in Photosynthetic Antenna Complex of Green Sulfur Bacteria: Efficiency under Natural Sunlight Pumping. [PDF]
Valzelli A +3 more
europepmc +1 more source
Objective To investigate the association between rheumatoid arthritis (RA) and coronary artery calcium (CAC) prevalence, incidence, and progression over four years in adults without prior cardiovascular disease. Methods A case‐cohort study within the Brazilian Longitudinal Study of Adult Health (ELSA‐Brasil) included 585 participants (86 patients with ...
Patrícia Fonseca Estrada +7 more
wiley +1 more source
Evidence of static quenching in the photoredox activity of perylene diimide radical anions: implications for consecutive photoinduced electron transfer photocatalysis. [PDF]
Sucre-Rosales E +2 more
europepmc +1 more source
Objective JAK inhibitors (JAKis) have shown promising effects in early‐phase studies of SSc. We aimed to assess the safety and explore effectiveness of JAKis compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the EUSTAR cohort was performed.
Stefano Di Donato +27 more
wiley +1 more source
Photocatalytic degradation of methyl orange at different pH values by NaYF<sub>4</sub>:Yb<sup>3+</sup>,Tm<sup>3+</sup>@TiO<sub>2</sub> microrod composite photocatalysts under NIR excitation. [PDF]
Tang Y, Zeng J.
europepmc +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Decoding structural rigidity and charge-transfer polarization in barbituric-acid-based donor-π-acceptor chromophores. [PDF]
Miryala K, Katdare M, Dey N.
europepmc +1 more source

