Results 51 to 60 of about 777,754 (321)

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

open access: yesFEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga   +6 more
wiley   +1 more source

Charge Photoaccumulation in Covalent Polymer Networks for Boosting Photocatalytic Nitrate Reduction to Ammonia

open access: yesAdvanced Science
In the design of photoelectrocatalytic cells, a key element is effective photogeneration of electron‐hole pairs to drive redox activation of catalysts.
Xinjia He   +4 more
doaj   +1 more source

Excited State Dynamics with Quantum Trajectories

open access: yesCHIMIA, 2012
Nuclear quantum dynamics beyond the Born-Oppenheimer approximation is performed using quantum trajectories. Withintheadiabaticrepresentationoftheelectronicstates, NABDY(NonAdiabaticBohmianDYnamics) is used in combination with DFT and LR-TDDFT to
Basile F. E. Curchod   +2 more
doaj   +1 more source

Identification of excited states in 140Dy

open access: yesAIP Conference Proceedings, 2002
Excited structures in the proton-rich nucleus 140Dy have been established following the decay of an 8- isomer. The excitation energy of the isomer is established to be 2.16 MeV with a half-life of 7.3 ± 1.5 ps. The isomer decays into the yrast line at the 8+ state, revealing a rotational band with a deduced deformation of β2 = 0.24(3).
D. M. Cullen   +21 more
openaire   +3 more sources

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Frequency-resolved photon-electronic spectroscopy for excited state population detection [PDF]

open access: yesOptics Letters Vol. 43, Issue 23, pp. 5725-5728 (2018), 2018
Atomic excitation to excited states in strong laser field is the key to high-order harmonic generation below ionization threshold, yet remains unclear mainly due to the lack of proper detection methods. We propose a frequency-resolved photon-electron spectroscopy technique to reconstruct population of excited states with the second delayed laser pulse.
arxiv   +1 more source

Superatomic Rydberg State Excitation

open access: yesSSRN Electronic Journal, 2021
Superatomic molecular orbitals (SAMOs) have symmetries (angular quantum numbers) similar to those of atoms, and thus, it is possible to realize Rydberg state excitations (RSEs) in superatomic molecules. In this Letter, the feasibility of superatomic Rydberg state excitation (SRSE) is explored using gold superatoms based on first-principles calculations.
Zheng Liu   +5 more
openaire   +5 more sources

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Exploiting the excited state

open access: yesPhysica B: Condensed Matter, 2003
AbstractThe major ideas of microelectronics are associated with the electronic ground state, or with states thermally accessible at modest temperatures. Photonics, and many realisations of quantum devices, require excited states. Excited states are the basis of new processing methods for organic and inorganic systems.
openaire   +2 more sources

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

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