Results 61 to 70 of about 1,214,634 (346)

Amide Activation in Ground and Excited States

Molecules, 2018
Not all amide bonds are created equally. The purpose of the present paper is the reinterpretation of the amide group by means of two concepts: amidicity and carbonylicity.
Ervin Kovács, Balázs Rózsa, Attila Csomos, Imre G. Csizmadia, Zoltán Mucsi   +4 more
doaj   +1 more source

Singlet Excited States of Anions with Higher Main Group Elements

, 2013
Previous studies have shown that dipole-bound excited states exist for certain small anions. However, valence excited states have been reported for some closed-shell anions, but those with singlet valence excited states have, thus far, contained a single
Fortenberry, Ryan C.
core   +1 more source

Optimization of ground and excited state wavefunctions and van der Waals clusters [PDF]

, 2000
A quantum Monte Carlo method is introduced to optimize excited state trial wavefunctions. The method is applied in a correlation function Monte Carlo calculation to compute ground and excited state energies of bosonic van der Waals clusters of upto seven
Andrei Mushinski, B. Bernu, C. J. Umrigar, C. J. Umrigar, C. J. Umrigar, D. Blume, D. Blume, D. H. Zhang, D. M. Ceperley, D. M. Leitner, G. H. Golub, J. de Boer, J. H. Hetherington, J. K. L. MacDonald, M. Caffarel, M. Caffarel, M. Foulkes, M. Meierovich, M. P. Nightingale, M. P. Nightingale, M. P. Nightingale, V. Melik-Alaverdian, Vilen Melik-Alaverdian, W. H. Press, W. R. Brown   +24 more
core   +3 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Exchange couplings in the magnetic molecular cluster Mn12Ac

, 2002
The magnetic properties of the molecular cluster Mn12Ac are due to the four Mn3+ ions which have spins S=3/2 and the eight Mn4+ ions with spins S=2. These spins are coupled by superexchange mechanism.
A. Caneschi, A.A. Mukhin, A.K. Zvezdin, A.L. Barra, A.M. Gomes, B. Barbara, C. Raghu, D. Gatteschi, I. Mirebeau, M. Hennion, M. Verdaguer, N. Regnault, O. Golinelli, R. Sessoli, R. Sessoli, R. Sessoli, T. Lis, Th. Jolicœur   +17 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Switching of photocurrent polarity in electrochemical cells with light via an excited state proton transfer mechanism [PDF]

, 2023
Anna Yuchnovsky, Yaniv Shlosberg, Noam Adir, Nadav Amdursky   +3 more
openalex   +1 more source

Unexpected properties of the first excited state of non-bipartite Heisenberg spin rings

, 2000
Systematic properties of the first excited state are presented for various ring sizes and spin quantum numbers which are only partly covered by the theorem of Lieb, Schultz and Mattis.
Schnack, J.
core   +2 more sources