Results 101 to 110 of about 2,444,021 (248)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

La frontera como mecanismo de exclusión social [PDF]

open access: yes, 2015
Para el caso latinoamericano, se ha hecho presente históricamente una diferenciación cultural que ha sobrepasado la diferenciación física que imponen de los límites territoriales, y ésta sienta sus bases en el mosaico multicultural que constituye al ...
MENDEZ RAMIREZ, JOSE JUAN   +3 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Sociedades fracturadas : la exclusión social en Centroamérica [PDF]

open access: yes, 2017
El presente texto tiene un doble origen. Por un lado, desde hace ya varios años en la Facultad Latinoamericana de Ciencias Sociales (FLACSO), Sede de Costa Rica, se ha venido desarrollando un enfoque sobre las carencias materiales de la población ...
Fernández Montero, Diego - Autor/a   +3 more
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Excepciones a la exclusión de la prueba ilícita [PDF]

open access: yes, 2014
El trabajo desarrolla la regla de la exclusión de la prueba ilícita desde una perspectiva comparada, estableciendo su origen, se observa como se ha ido extendiendo a otros países con ordenamientos jurídicos y sistemas procesales diferentes, a través de ...
Galeano Porras, Erika Adriana
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Psicología y discapacidad: un encuentro desde el paradigma social

open access: yesRevista Costarricense de Psicología, 2014
El tema de la discapacidad ha sido abordado desde diversos paradigmas o modelos que han dictado el modo de brindar atención a personas con esta condición.
Lucrecia Alfaro-Rojas
doaj  

Categorías sociales y personas en situación de exclusión. Una aproximación desde el País Vasco [PDF]

open access: yes, 2005
During the last twenty five years the social changes gave rise to social exclusion is seen as a new social problem in Western societies. Although several sectors of population are included under the label of «social exclusion», social sciences have not ...
Raya Diez, Esther
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy