Results 141 to 150 of about 2,118,026 (309)
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
Nulidad de matrimonio (Exclusión del matrimonio, defecto de discreción de juicio e incapacidad de asumir las obligaciones). Sentencia [PDF]
, 2001 Roberto Serres López de Guereñú
openalex +1 more source
A study about social exclusion in the area of Caudal in the Principality of Asturias (Spain) [PDF]
, 2010 En el artículo se describe y comenta una experiencia práctica de análisis del perfil de exclusión social en la comarca del Caudal del Principado de Asturias. A modo de introducción se comentan las principales funciones de los E.T.S.S., la normativa sobre
Rodríguez Fernández, Juan Ramón
core +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Sobre los complejos procesos de exclusión e integración en España
, 1969 Miguel Beas Miranda
openalex +2 more sources
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
Puntos de articulación entre violencia social, exclusión y violencia escolar
, 1970 Guadalupe Poujol Galván
openalex +2 more sources
Violencia, pobreza y exclusión social [PDF]
, 2002 Esperanza Linares Márquez de Prado
openalex +1 more source