Results 41 to 50 of about 1,740,907 (198)

Una aproximación a las situaciones de desprotección social en la población infanto-juvenil de origen extranjero, sobrevenidas en el actual contexto de crisis económica y precarización del Sistema de Protección a la Infancia y Adolescencia de Navarra.

Cuadernos de Trabajo Social, 2014
¿Deben asociarse las situaciones de desprotección-conflicto social únicamente a la mayor o menor capacidad protectora de las figuras parentales? O, por el contrario, ¿deberíamos tener en cuenta la presencia de otras situaciones sobrevenidas? Situaciones,
Miguel Ángel Gurbindo Marin
doaj   +1 more source

Evaluation of the Utility of Baseline Echocardiogram in Patients With Standard Risk Precursor B‐Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
Abstract Background A routine baseline echocardiogram is often obtained prior to anthracycline administration in children with cancer. The utility of baseline echocardiogram is unclear in patients with standard risk B‐cell acute lymphoblastic leukemia (SR B‐ALL) as their anthracycline cumulative dose is low.
Ziyad Alrajhi, Alice Pozza, Luc Mertens, Adam Paul Yan, Sarah Alexander   +4 more
wiley   +1 more source

Acceso a la educación y factores de vulnerabilidad en las personas con discapacidad.

Voces de la educación, 2020
En este artículo, presentamos algunos de los factores que inciden en la vulnerabilidad educativa de las personas con discapacidad. Partimos de la discusión sobre lo que entendemos por vulnerabilidad, para posteriormente analizar algunas cuestiones que ...
Judith Pérez Castro
doaj  

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Apuntes respecto de la validez de los acuerdos procesales que condicionan el acceso a la anulación de laudo a la constitución de una garantía en el ordenamiento jurídico peruano

Thēmis, 2020
En el ordenamiento jurídico peruano es posible que las partes celebren acuerdos procesales que condicionen el acceso a la anulación del laudo arbitral a la constitución de una garantía.
Héctor Campos García
doaj  

Bases de análisis e intervención con la minoría gitana en los Servicios Sociales

Cuadernos de Trabajo Social, 2012
No son recomendables atajos en la intervención social y mucho menos en los Servicios Sociales de base cuyos cometidos, demandas recibidas y prestaciones conciernen sobremanera a las personas y grupos con más desventajas sociales.
Miguel Arenas Martínez
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source