Results 71 to 80 of about 20,644,730 (303)

Preciso estudar para ser alguém: memória e representações sociais da educação escolar

Paidéia (Ribeirão Preto), 2008
As teorias que tratam da memória social e das representações sociais entendem essas modalidades de manifestação mental como construídas e compartilhadas socialmente pelos grupos de vivências semelhantes.
Luciene Alves Miguez Naiff, Celso Pereira de Sá, Denis Giovanni Monteiro Naiff   +2 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

A critical review and development of a conceptual model of exclusion from social relations for older people

European Journal of Ageing, 2019
Social exclusion is complex and dynamic, and it leads to the non-realization of social, economic, political or cultural rights or participation within a society. This critical review takes stock of the literature on exclusion of social relations.
V. Burholt, B. Winter, M. Aartsen, C. Constantinou, L. Dahlberg, Villar Feliciano, J. de Jong Gierveld, Sofie Van Regenmortel, C. Waldegrave   +8 more
semanticscholar   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Latinoamericanos en España : la integración en la Europa de la exclusión social [PDF]

, 2005
Este trabajo se estructura en cuatro puntos generales. En primer lugar, se realiza una reflexión general sobre migraciones internacionales, enfoques teóricos y procesos de desarrollo, para, más tarde, realizar una aproximación al número y las ...
La Parra Casado, Daniel, Mateo-Perez, Miguel-A, La Parra-Casado, Daniel, Mateo Pérez, Miguel Ángel   +3 more
core   +1 more source

Area effects on the level and development of social exclusion in later life.

Social Science & Medicine (1967), 2019
Social exclusion in later life is associated with decreased quality of life and poorer health outcomes. Reducing the number of people at risk of exclusion is a key theme in European social policy, but there is limited understanding of the relationship ...
J. Prattley, T. Buffel, Alan Marshall, J. Nazroo   +3 more
semanticscholar   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Delito, violencia y exclusión social

Question, 2011
En Sociología del delito amateur, Gabriel Kessler se propone un abordaje del delito y la violencia como parte de una reflexión más amplia sobre la cuestión social.
Claudiana Shirli Pereson
doaj