Results 41 to 50 of about 4,057,435 (306)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Juggler's Exclusion Process [PDF]

open access: yesJournal of Applied Probability, 2012
Juggler's exclusion process describes a system of particles on the positive integers where particles drift down to zero at unit speed. After a particle hits zero, it jumps into a randomly chosen unoccupied site. We model the system as a set-valued Markov process and show that the process is ergodic if the family of jump height distributions is ...
Leskelä Lasse, Varpanen Harri
openaire   +3 more sources

Understanding social exclusion [PDF]

open access: yes, 2002
This CASEbrief summarises 'Understanding Social Exclusion' edited by John Hills, Julian Le Grand and David Piachaud, published by Oxford University ...
Hills, John   +2 more
core  

A dynamically extending exclusion process

open access: yes, 2007
An extension of the totally asymmetric exclusion process, which incorporates a dynamically extending lattice is explored. Although originally inspired as a model for filamentous fungal growth, here the dynamically extending exclusion process (DEEP) is ...
Antal T   +8 more
core   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait   +23 more
wiley   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Ways of rethinking inclusion for disabled students in Higher Education

open access: yesJournal of Learning Development in Higher Education, 2023
The word ‘inclusion’ now frequently appears in the marketing strategies of many UK universities, despite the equivocal ways the term is used across the sector (Koutsouris et al., 2022).
Julian Ingle
doaj   +1 more source

EXCLUSION AND EXCLUSIVITY IN PROPERTY LAW [PDF]

open access: yesUniversity of Toronto Law Journal, 2008
In this article, I propose a model for understanding the concept of ownership that I call the ‘exclusivity model.’ Like many of the contemporary critics of the ‘bundle of rights’ approach to ownership, I insist that ownership is a legal concept with a well-defined structure. I differ from most of them, however, in the model of ownership that I believe
openaire   +1 more source

Dynamic Singularities in Cooperative Exclusion

open access: yes, 2011
We investigate cooperative exclusion, in which the particle velocity can be an increasing function of the density. Within a hydrodynamic theory, an initial density upsteps and downsteps can evolve into: (a) shock waves, (b) continuous compression or ...
Alan Gabel   +10 more
core   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman   +8 more
wiley   +1 more source

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