Results 121 to 130 of about 140,437 (320)
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Executable First-Order Queries in the Logic of Information Flows [PDF]
Aamer, Heba +4 more
core +1 more source
ROPocop - Dynamic Mitigation of Code-Reuse Attacks
Control-flow attacks, usually achieved by exploiting a buffer-overflow vulnerability, have been a serious threat to system security for over fifteen years.
Bodden, Eric, Follner, Andreas
core +1 more source
Microwave Frequency Synthesizer Executed in Microelectronic Circuits [PDF]
Martirosov Vladimir E. +1 more
openalex +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Read Book [PDF] Crafting and Executing Strategy: Concepts and Readings (Crafting & Executing Strategy: Text and Readings) Full Pages
openalex +2 more sources
XCorpus – An executable Corpus of Java Programs. [PDF]
Jens Dietrich +3 more
openalex +1 more source
An assessment of the autism neuroimaging literature for the prospects of re-executability [PDF]
Steven M. Hodge +4 more
openalex +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

