Results 21 to 30 of about 49,891 (172)

Executable network of SARS-CoV-2-host interaction predicts drug combination treatments

npj Digital Medicine, 2022
The COVID-19 pandemic has pushed healthcare systems globally to a breaking point. The urgent need for effective and affordable COVID-19 treatments calls for repurposing combinations of approved drugs.
Rowan Howell, Matthew A. Clarke, Ann-Kathrin Reuschl, Tianyi Chen, Sean Abbott-Imboden, Mervyn Singer, David M. Lowe, Clare L. Bennett, Benjamin Chain, Clare Jolly, Jasmin Fisher   +10 more
doaj   +1 more source

Dynamic Slicing by On-demand Re-execution [PDF]

arXiv, 2022
In this paper, we propose a novel approach that aims to offer an alternative to the prevalent paradigm to dynamic slicing construction. Dynamic slicing requires dynamic data and control dependencies that arise in an execution. During a single execution, memory reference information is recorded and then traversed to extract dependencies.
arxiv  

Visualizing Trace Variants From Partially Ordered Event Data [PDF]

, 2021
Executing operational processes generates event data, which contain information on the executed process activities. Process mining techniques allow to systematically analyze event data to gain insights that are then used to optimize processes. Visual analytics for event data are essential for the application of process mining.
arxiv   +1 more source

Executable choreographies applied in OPERANDO [PDF]

Computer Science Journal of Moldova, 2016
The objective of this paper is to present the software architecture used for the OPERANDO privacy platform, funded by the European Union in a Horizon 2020 project. For integration, OPERANDO is using SwarmESB, an open source Enterprise Service Bus (ESB)
Sinica Alboaie, Lenuta Alboaie, Mircea-Florin Vaida, Cristina Olariu   +3 more
doaj  

Making an executable paper with the Python in Heliophysics Community to foster open science and improve reproducibility

Frontiers in Astronomy and Space Sciences, 2023
We share the story of how we made this paper, the first executable paper in Heliophysics, through cross-disciplinary collaboration to highlight the benefits of our process.
Shawn Polson, Rebecca Ringuette, Rebecca Ringuette, Lutz Rastaetter, Eric Grimes, Jonathan Niehof, Nicholas A. Murphy, Yihua Zheng   +7 more
doaj   +1 more source

Towards Synthesizing Executable Models in Biology

Frontiers in Bioengineering and Biotechnology, 2014
Over the last decade, executable models of biological behaviors have repeatedly provided new scientific discoveries, uncovered novel insights, and directed new experimental avenues.
Jasmin eFisher, Jasmin eFisher, Rastislav eBodik   +2 more
doaj   +1 more source

On (the Lack of) Code Confidentiality in Trusted Execution Environments [PDF]

arXiv, 2022
Trusted Execution Environments (TEEs) have been proposed as a solution to protect code confidentiality in scenarios where computation is outsourced to an untrusted operator. We study the resilience of such solutions to side-channel attacks in two commonly deployed scenarios: when a confidential code is a native binary that is shipped and executed ...
arxiv  

IQCELL: A platform for predicting the effect of gene perturbations on developmental trajectories using single-cell RNA-seq data.

PLoS Computational Biology, 2022
The increasing availability of single-cell RNA-sequencing (scRNA-seq) data from various developmental systems provides the opportunity to infer gene regulatory networks (GRNs) directly from data.
Tiam Heydari, Matthew A Langley, Cynthia L Fisher, Daniel Aguilar-Hidalgo, Shreya Shukla, Ayako Yachie-Kinoshita, Michael Hughes, Kelly M McNagny, Peter W Zandstra   +8 more
doaj   +1 more source

Validating Avionics Conceptual Architectures with Executable Specifications [PDF]

Journal of Systemics, Cybernetics and Informatics, 2012
Current avionics systems specifications, developed after conceptual design, have a high degree of uncertainty. Since specifications are not sufficiently validated in the early development process and no executable specification exists at aircraft level ...
Nils Fischer, Horst Salzwedel
doaj  

Dynamic Socio-technical System Design based on Stakeholder Interaction

Complex Systems Informatics and Modeling Quarterly, 2015
In order to directly involve stakeholders in socio-technical system design, we argue for streamlining executable process specifications with business process modeling.
Albert Fleischmann, Werner Schmidt, Christian Stary   +2 more
doaj   +1 more source