Results 161 to 170 of about 258,275 (298)

Systematic Exploration of 3D Concrete Printing Parameters for Conformal Printing on Sloped Surfaces

Advanced Robotics Research, EarlyView.
A conformal slicing algorithm is developed for robotic 3D concrete printing (3DCP) on sloped surfaces as a first step toward printing slab‐on‐grade foundations on uneven terrain. Systematic experiments quantify the effects of nozzle speed, extrusion rate, and toolpath direction on filament dimension and stability.
Paniz Farrokhsiar, Benay Gursoy, Jose Pinto Duarte   +2 more
wiley   +1 more source

Artificial Intelligence as a Disruptive Force in Pharmaceutical Innovation: Transforming Discovery, Development, and Manufacturing. [PDF]

Drug Des Devel Ther
Herdiana Y, Mohammed AFA, Kautsar AP, Sopyan I, Wathoni N.   +4 more
europepmc   +1 more source

ELABELA Targets Mitochondria to Modulate Heart Development

Advanced Science, EarlyView.
The role of peptide ELABELA (ELA) in cardiomyocyte apoptosis and congenital heart disease (CHD) is unclear. ELA deficiency caused cardiomyocyte apoptosis and CHD. A novel ELA‐APJ‐AKT‐BCL2/BAX axis in regulating mitochondrial function and contributing to CHD pathogenesis was established.
Jian Wang, Qingjie Wang, Zhikang Xu, Shuang Zhou, Yue Zhou, Junjie Yang, Lingfeng Tong, Zhuo Meng, Mei Yang, Wen Zhao, Tie Yang, Hualin Wang, Jun Zhang, Rubin Tan, Lei Wang, Yuqiang Huang, Bin Zhou, Sun Chen, Bing Zhang, Jinxiang Yuan, Jianyuan Zhao, Alex F. Chen, Kun Sun   +22 more
wiley   +1 more source

Perceptions of Medical Students' Unprofessional Behaviors Among Faculty Members and Medical Students: A Cross-Sectional Study at a Japanese Medical School. [PDF]

Adv Med Educ Pract
Yamashita S, Sakamoto M, Yaita S, Inoue K, Mizoguchi Y, Hoshino Y, Yamaguchi M, Ide N, Katsuki NE, Tago M, Miyata Y, Oda Y.   +11 more
europepmc   +1 more source

Targeting UXS1‐Dependent Glucuronate Detoxification Potentiates Metformin's Anti‐Tumor Efficacy in Lung Adenocarcinoma

Advanced Science, EarlyView.
This study reveals that metformin promotes glucuronic acid metabolism in lung adenocarcinoma by activating UGDH S476 phosphorylation and enhancing the conversion of UDPG to UDPGA based on metabolomics analysis. Through compound virtual screening, it is found that plantainoside targeting UGDH downstream UXS1 leads to UDPGA toxicity accumulation ...
Qihai Sui, Zhencong Chen, Guangyao Shan, Zhengyang Hu, Xing Jin, Jiaqi Liang, Yanjun Yi, Jiacheng Yin, Haochun Shi, Xifei Jiang, Junjie Xi, Zongwu Lin, Cheng Zhan, Fenghao Sun, Wei Jiang   +14 more
wiley   +1 more source

Responsible use of large language models in gastroenterology and hepatology. [PDF]

Ther Adv Gastroenterol
Khanna S.
europepmc   +1 more source

RIGHTS AND OBLIGATIONS OF A LAWYER DURING THE EXECUTION OF COURT DECISIONS

Juridical scientific and electronic journal, 2023
openaire   +1 more source

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

Advanced Science, EarlyView.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li, Yuying Zhang, Jingjing Wang, Qianqian Zhang, Hailiang Sun, Fanhua Wei   +5 more
wiley   +1 more source

Data visiting governance: a conceptual framework. [PDF]

Hum Genomics
Thaldar D.
europepmc   +1 more source

Opinion of the Commission pursuant to Article 189 b(2)(d) of the EC Treaty, on the European Parliament’s amendments to the Council’s common position regarding the proposal for a European Parliament and Council Directive on cross-border credit transfers. COM (96) 172 final, 19 April 1996 [PDF]

, 1996

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